research Uncharted Waters: The Impact of NGS and Machine Learning on Forensic Science
New DNA analysis and machine learning are advancing forensic science, improving accuracy and expanding into non-human applications.
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research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Nilotinib-Induced Generalized Keratosis Pilaris: Report of a Rare Case
Nilotinib can cause generalized keratosis pilaris.
research A Critical Evaluation of Evaluations for Long-Form Question Answering
Current methods can't accurately predict which long-form answers people prefer; evaluations should consider different answer qualities separately.
research Novel Splicing-Site Mutation in DCAF17 Gene Causing Woodhouse-Sakati Syndrome in a Large Consanguineous Family
A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.
research The Potential Impact of Melanosomal pH and Metabolism on Melanoma
Melanin may help melanoma cells grow by aiding their metabolism.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may rarely cause hair loss.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies
Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
research Dermatological Diseases from a Genetic Perspective
New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
research Clinical and Analytical Evaluation of LC-MS Methods for Plasma Renin Activity and Aldosterone
The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.
research Role of Epigallocatechin-3-Gallate from Green Tea in Iron Chelation and Endoplasmic Reticulum Stress Pathway in Colorectal Cancer Cells
Green tea compound EGCG could potentially treat colorectal cancer by removing iron and causing stress in cancer cells leading to their death.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may cause hair loss in rare cases.
research Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth
Three-dimensional culture helps dermal papilla cells grow new human hair follicles.
research Germline Mutation in ATR in Autosomal-Dominant Oropharyngeal Cancer Syndrome
A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors
Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.
research Direct-Acting Vasodilators
Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series
Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
research International Evidence-Based Guideline on Assessment and Management of PCOS—A Nordic Perspective
The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.
research Patient Prioritization of Items to Develop the Patient-Reported Impact of Dermatological Diseases Measure: A Global Delphi Study
The study created a 27-item measure to assess the impact of skin diseases.
research Two Mutations at KRT74 and EDAR Synergistically Drive the Fine-Wool Production in Chinese Sheep
Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.
research Skin-Specific Transgenic Overexpression of Ovine β-Catenin in Mice
Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
research Imatinib-Induced Classical Lichen Planopilaris in Blaschko-Linear Distribution Leading to Cicatricial Alopecia
Imatinib can cause hair loss due to lichen planopilaris.
research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and Across the Skin
Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.
research Production and Characterization of Human Hair Keratin Bioplastic Films With Novel Plasticizers
Human hair was used to make biodegradable plastic films that could be useful for packaging and disposable products.
research EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia
A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.
research Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture
Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.