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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair growth and pigmentation in mice involve specific stages crucial for research.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Sebocytes play a key role in controlling androgen levels in human skin.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Special fiber materials boost the healing properties of certain stem cells.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Latanoprost can make eyelashes longer, thicker, and darker.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Humans lost body hair relatively recently in evolution.

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

Cathepsin L is essential for normal hair growth and development.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.