4 citations
,
January 2013 in “PubMed” In this study, testosterone and finasteride were found to increase insulin and zinc levels while decreasing chromium levels in male adult rats, suggesting potential effects on the glucose cycle.
4 citations
,
January 2013 in “Dissolution Technologies” This study optimized and validated a dissolution test method for immediate-release finasteride capsules, highlighting the need for an official standard due to variability in commercial products.
4 citations
,
January 2012 in “Medical Hypotheses” This article reviews potential mechanisms by which Finasteride might enhance mesenchymal stem cell viability and differentiation post-transplant, suggesting a supportive role in myocardial infarction therapy, yet reports no clinical results.
4 citations
,
December 2011 in “Drug Research” This study found that two different 5 mg finasteride tablet formulations are bioequivalent in terms of the rate and extent of absorption in healthy volunteers.
4 citations
,
October 2009 in “International Journal of Endocrinology and Metabolism” This study found that both Diane 35 plus spironolactone and Diane 35 plus finasteride were equally effective and safe for treating hirsutism and acne in Indian women over a 12-month period.
4 citations
,
April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
4 citations
,
September 2006 in “European Journal of Clinical Pharmacology” This study concluded that finasteride 1 mg does not significantly affect the metabolism of omeprazole in young healthy Japanese male extensive or poor metabolizers for CYP2C19.
4 citations
,
February 2004 in “Journal of Clinical Gastroenterology” Finasteride doesn't raise acute pancreatitis risk.
4 citations
,
June 2003 in “Fertility and Sterility” In this pilot study, finasteride increased testosterone/dihydrotestosterone and progesterone/dihydroprogesterone ratios in normal ovulatory women but did not alter ovulation or gonadotropin secretion.
4 citations
,
January 2002 in “Indian Journal of Pharmaceutical Sciences” This study developed a precise and reproducible method for estimating finasteride in tablet formulations using a colorimetric reaction with specific reagents.
4 citations
,
November 2001 in “PubMed” This study observed that 54% of men with male pattern hair loss showed hair growth improvement in the vertex region after 6 months of treatment with oral finasteride.
4 citations
,
September 1994 in “Xenobiotica” Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.
4 citations
,
February 1996 in “Postgraduate Medical Journal” Finasteride linked to skin inflammation.
4 citations
,
July 2018 in “International Journal of Research in Dermatology” This study found that among patients with stage III and IV androgenic alopecia, 83% of those using topical 5% minoxidil with topical 0.1% finasteride showed improved hair density, suggesting it may reduce the need for long-term oral finasteride.
3 citations
,
September 2023 in “International journal of impotence research” The authors concluded that finasteride and dutasteride might have serious side effects, including persistent sexual dysfunction for some, necessitating further research and vigilant risk-benefit analysis.
3 citations
,
July 2022 in “BMC chemistry” This study introduced and validated new spectrophotometric methods to simultaneously determine finasteride and tadalafil in Entadfi™ capsules with high sensitivity and without interference from excipients.
3 citations
,
April 2022 in “Neuroscience Letters” In this animal study, finasteride significantly improved autism-like symptoms in rats by reversing biochemical markers and enhancing behaviors, potentially due to its antioxidant and anti-androgen effects.
3 citations
,
April 2021 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.
3 citations
,
September 2019 in “American Journal of Men's Health” This study suggests that continuing finasteride therapy after mastectomy does not significantly affect gynecomastia recurrence in men taking finasteride for alopecia.
3 citations
,
April 2019 in “Human & Experimental Toxicology” This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.
3 citations
,
September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
3 citations
,
July 2018 in “African Journal of Urology” This study found that six weeks of finasteride therapy before TURP reduced intraoperative blood loss and improved early postoperative quality of life in patients with benign prostatic hyperplasia.
3 citations
,
June 2018 in “International Journal of Clinical Pharmacy” In this case report, maternal use of finasteride during early pregnancy was not associated with external genitalia abnormalities in a male infant, but the findings are limited to one case and broader safety conclusions cannot be drawn.
3 citations
,
February 2017 in “Archives of Medical Science” This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.
3 citations
,
December 2016 in “Universal journal of pharmaceutical research” This study concluded that Finasteride can be effectively delivered in matrix tablets using different polymer ratios for sustained release.
3 citations
,
May 2016 in “Behavioural Brain Research” This study suggests that altering levels of the neurosteroid allopregnanolone during neonatal stages in rats may impact alcohol consumption and dopamine release in adulthood, indicating potential effects on alcohol reward properties.
3 citations
,
February 2016 in “Scandinavian journal of urology” This study found notable differences in finasteride use among the Nordic countries, with higher prevalence in Finland and Sweden compared to Denmark and Norway.
3 citations
,
October 2015 in “Human Psychopharmacology-clinical and Experimental” In this study, finasteride was found not to be associated with changes in sleep spindle activity or morphology in men undergoing sleep studies.
3 citations
,
October 2015 in “PubMed” This study found that sexual side effects occurred in a small percentage of patients using combined finasteride and minoxidil, but these were not common reasons for discontinuing treatment.
3 citations
,
October 2015 in “PubMed” This study found an increased risk of intraoperative iris billowing in rabbits treated with finasteride, similar to those treated with tamsulosin, suggesting further research in humans is needed.