7 citations
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January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
7 citations
,
October 2017 in “Artificial Cells Nanomedicine and Biotechnology” This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.
7 citations
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May 2015 in “Journal of The American Academy of Dermatology” Finasteride helps treat frontal fibrosing alopecia, improving or stabilizing the condition in many patients.
7 citations
,
April 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
7 citations
,
April 2015 in “JAMA Dermatology” This text does not provide any research findings or results from a study.
7 citations
,
March 2015 in “The American Journal of the Medical Sciences” This study found that finasteride reduced VEGF expression and microvessel density in the renal tissue of diabetic rats, suggesting its potential for treating diabetic microvascular complications.
7 citations
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November 2014 in “Clinical Therapeutics” This study observed that coadministration of finasteride and tamsulosin in healthy Chinese males appears unlikely to result in a clinically significant pharmacokinetic interaction.
7 citations
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January 2014 in “Rinshō shinkeigaku” This report describes two cases of stroke associated with finasteride use for male-pattern hair loss, suggesting a potential link to thrombosis due to increased estrone and estradiol levels.
7 citations
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January 2012 in “PubMed” In this study, azelaic acid 20% and finasteride increased BCL-2 protein expression and decreased bax protein expression in rats after skin flap surgery, suggesting a potential antiapoptotic role in reducing ischemia-induced damage.
7 citations
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October 2009 in “Journal of the American Geriatrics Society” This study found that finasteride may reduce inappropriate sexual behaviors in geriatric patients with vascular dementia and benign prostate hyperplasia without serious side effects, though some patients required additional medications.
7 citations
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May 2008 in “PubMed” This study found that patients treated with dutasteride were significantly less likely to experience acute urinary retention and prostate-related surgeries compared to those treated with finasteride.
7 citations
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April 2007 in “PubMed” This case report describes a novel occurrence of erythema annulare centrifugum associated with finasteride use for androgenetic alopecia, which resolved upon discontinuation and recurred with reintroduction.
7 citations
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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
7 citations
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February 2003 in “Gynecological Endocrinology” This study found that finasteride treatment significantly reduced hirsutism and dihydrotestosterone levels in women with idiopathic hirsutism or polycystic ovary syndrome over six months.
7 citations
,
May 2002 in “Hair transplant forum international” This article reviews long-term data on the efficacy and safety of finasteride over five years but reports no new clinical results.
7 citations
,
July 1995 in “PubMed” Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
7 citations
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April 1995 in “Endocrinology” This study concluded that finasteride treatment did not adversely affect bone development or density in male rats, suggesting selective DHT deficiency is not harmful to the skeleton.
6 citations
,
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review evaluates the use of 5α-reductase inhibitors in feminising hormone therapy, finding their additive feminising benefits unclear due to their specific action on testosterone conversion, with concerns highlighted regarding limited supporting evidence and safety signals, particularly for psychiatric and sexual effects.
6 citations
,
March 2021 in “International Journal of Pharmaceutics” This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.
6 citations
,
January 2021 in “International Journal of Molecular Sciences” This study suggests that finasteride treatment in male rats can lead to changes in liver carbohydrate metabolism and may result in metabolic disruptions and liver steatosis in their offspring.
6 citations
,
August 2020 in “Journal of Pharmaceutical Innovation” This study found that a lipid nanoemulsion-based gel of finasteride for topical use improved hair growth and was effective against alopecia, with slow skin permeation and increased efficacy compared to a testosterone-treated group.
6 citations
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January 2020 in “Dermatology” This study suggests that men under 40 who develop persistent sexual side effects and insomnia after using finasteride for alopecia may be at increased risk of suicide.
6 citations
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June 2019 in “Skin Research and Technology” In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.
6 citations
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March 2019 in “International Journal of Molecular Medicine” This study found that finasteride-loaded microspheres effectively treated androgenic alopecia in a mouse model, showing similar hair growth effects to orally-administered finasteride.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
6 citations
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February 2016 in “Journal of Microencapsulation” This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.
6 citations
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January 2016 in “International Journal of Trichology” This case study suggests that patients with acquired progressive kinking of the hair may benefit from finasteride treatment due to an increased risk of developing androgenetic alopecia.
6 citations
,
April 2015 in “Behavioural Brain Research” In this study, finasteride was found to potentiate stress-induced disruption in sensory gating of rats by neutralizing the increase in allopregnanolone levels after acute stress.
6 citations
,
June 2014 in “PubMed” This study concluded that transurethral seminal vesiculoscopy combined with finasteride is a safe and effective treatment for recurrent hemospermia in the observed patients.
6 citations
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April 2014 in “PubMed” This case report hypothesizes that finasteride 1mg daily may influence melasma development in men by affecting estrogen and progesterone levels in the skin.