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330-360 / 1000+ resultsresearch Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature
This review found that finasteride monotherapy for managing LUTS/BPH significantly reduced prostate volume and improved symptoms, with sexual dysfunctions reported as notable side effects compared to placebo, but emphasizes the need for more comprehensive studies.
research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota
This study found that ranitidine and finasteride may have cardiovascular and renal protective effects in mice by inhibiting TMAO synthesis and improving gut microbiota composition.
research Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness?
This paper discusses the first reported case of post-finasteride syndrome in a long-term dermatotrichology setting, occurring in a 25-year-old male after dutasteride treatment, and highlights possible links to mental health disorders.
research The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
In this animal study, researchers found that finasteride may offer neuroprotective benefits as a post-ischemic treatment for strokes in aged male rats, suggesting its potential as a therapeutic agent in this context.
research Finasteride Topical Delivery Systems for Androgenetic Alopecia
In this study, researchers reviewed literature on topical delivery of finasteride for androgenetic alopecia, finding that liposomal gels with specific additives showed the highest skin permeation rates, suggesting potential for reducing systemic side effects compared to oral formulations.
research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia
This study identified differences in adverse symptoms among patients with post-finasteride syndrome based on short and long androgen receptor gene polymorphisms.
research Exploring the neural mechanisms of finasteride: a proteomic analysis in the nucleus accumbens
This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.
research Evidence for the efficacy and safety of tadalafil and finasteride in combination for the treatment of lower urinary tract symptoms and erectile dysfunction in men with benign prostatic hyperplasia
This review examines the use of tadalafil and finasteride as a combined therapy for BPH, suggesting it may effectively reduce treatment-related sexual adverse events and improve symptom relief.
research Topical Formulations Containing Finasteride. Part II: Determination of Finasteride Penetration into Hair Follicles using the Differential Stripping Technique
This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
research HPTLC Method Validation for simultaneous determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form
This research discusses a validated HPTLC method for simultaneously determining Tamsulosin Hydrochloride and Finasteride in bulk and pharmaceutical dosage forms but reports no new clinical results.
research Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model
In this animal study, researchers found that finasteride reduced bacterial infection and inflammation in chronic bacterial prostatitis, with the greatest effect when combined with ciprofloxacin.
research Finasteride for prostatic disease: an updated and comprehensive review
This article reviews the use of finasteride for treating benign prostatic hyperplasia and its chemopreventive potential for prostate cancer, but it calls for further discussion on its preventive use in high-risk groups.
research How do we investigate haematuria and what role has finasteride?
Finasteride can treat prostatic haematuria, but its use is controversial.
research Finasteride Treatment May Not Prevent Telogen Effluvium After Minoxidil Withdrawal
This abstract provides no new data or findings as it is a placeholder text rather than a research summary.
research Finasterida: Diez Años De Uso Clínico. Revisión Sistemática De La Literatura
This review found strong evidence supporting Finasteride's effectiveness in reducing symptoms and improving quality of life in patients with larger prostate volumes, earning it a grade A recommendation for clinical use.
research A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets
Quickly get finasteride from tablets using easy methods.
research Finasteride Induced Gynecomastia
Finasteride can cause enlarged breasts.
research Co-loading of finasteride and baicalin in phospholipid vesicles tailored for the treatment of hair disorders
Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.
research Finasteride and androgenic alopecia; from therapeutic options to medical implications
This review explores the inconsistent therapeutic effects and side effects of finasteride for androgenic alopecia, highlighting the need for further research to better predict individual patient responses.
research Controversies in the treatment of androgenetic alopecia: The history of finasteride
This study reports that while topical minoxidil treatment showed a response in less than 40% of men after 24 weeks, oral finasteride stopped hair loss in over 80% of patients at 12 months; perceived sexual side effects of the latter may limit its use.
research Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice
This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.
research Finasteride does not prevent bladder cancer: A secondary analysis of the Medical Therapy for Prostatic Symptoms Study
In this study, researchers found no significant difference in bladder cancer incidence between men treated with finasteride and those given a placebo, suggesting that reduced dihydrotestosterone levels may not impact bladder cancer risk.
research Clinical efficacy of oral administration of finasteride at a dose of 2.5 mg/day in women with female pattern hair loss
This study found that 65.2% of female pattern hair loss patients showed significant hair growth improvement with a daily dosage of 2.5 mg finasteride, with better outcomes in patients with lower initial Ludwig scores and older age at onset.
research Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats
In this study, finasteride was found to inhibit the dopaminergic system and reduce open-field behaviors in adolescent male rats by decreasing dopamine levels and related proteins.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.
research Five-year efficacy of finasteride in 801 Japanese men with androgenetic alopecia
In this study, long-term finasteride treatment improved androgenetic alopecia in Japanese men, with younger age and less advanced disease at treatment start predicting better efficacy.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms. Does the Form X Exist?
This study found that the polymorphic forms I, II, and III of finasteride can be prepared purely, with form III being identical to what was previously referred to as form X.