126 citations
,
April 2015 in “Clinical, cosmetic and investigational dermatology” This review discusses best practices for minimizing complications with dermal fillers and provides guidance based on expert consensus, yet it reports no new clinical results.
101 citations
,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
97 citations
,
May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
10 citations
,
August 2020 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This minireview discusses the mechanisms of facial aging, examines current literature, and proposes filler injection protocols, but it reports no new clinical results.
9 citations
,
September 2021 in “Journal of cosmetic dermatology” This study suggests that hair loss and reduced arterial blood flow after hyaluronic acid filler injection in the temporal region may result from arterial compression rather than intra-arterial occlusion.
6 citations
,
June 2019 in “Journal of dermatology” Dermal fillers can cause hair loss, so dermatologists should be aware.
2 citations
,
March 2021 in “Pakistan veterinary journal” This study found that injecting hyaluronic acid fillers using a layered feathering technique temporarily corrected entropion and relieved associated symptoms in two dogs, an Old English Bulldog and a Chow Chow, maintaining eyelid positions for 6-8 months.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This case study reports significant hair regrowth in a 29-year-old female with filler-induced alopecia after treatment with concentrated growth factor injections, suggesting it as a promising alternative therapy to standard hyaluronidase injections.
May 2025 in “Oral Sciences Reports” This case study reports that a 45-year-old woman developed a painless nodule in the lower lip four weeks after receiving hyaluronic acid filler, which required surgical removal, highlighting the potential for delayed complications from lip augmentation procedures.
February 2025 in “International Journal of Dermatology” In this review, researchers examined pressure alopecia related to injectable treatments, identifying that injected volume can compress blood vessels, leading to hair loss through ischemia and inflammation, which emphasizes the need for targeted risk management and therapeutic strategies in dermatology.
January 2025 in “Journal of Dermatological Treatment” This study describes three cases of filler-induced alopecia with hair regrowth observed following treatments, emphasizing the importance of early intervention and understanding anatomical risks during cosmetic filler procedures.
April 2024 in “International Journal of Dermatology” This study reviewed cases of filler-induced alopecia and found that hyaluronic acid injections were most commonly associated with this condition, highlighting that hyaluronidase treatments can rapidly restore hair density, while alternative interventions need further exploration.
May 2018 in “Dermatologic Surgery” This journal overview highlights the expansive coverage of cosmetic and reconstructive skin surgery, but reports no new research findings.
36 citations
,
June 2009 in “Nanomedicine” This study found that fullerene nanomaterials can significantly enhance hair growth and increase hair follicle numbers in both shaved and bald mouse models, as well as in cultured human skin sections.
35 citations
,
August 2016 in “Experimental Dermatology” This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.
7 citations
,
January 2003 in “Journal of cosmetic and laser therapy” This study concluded that the Spa Touch system effectively retards hair regrowth, functioning like a "light razor" for quick and cost-effective epilation.
September 2025 in “International Journal of Molecular Sciences” This study found that injecting nu/nu mice with aqueous dispersion of unmodified fullerene C60 significantly stimulated hair growth compared to controls, suggesting its potential as a new therapeutic approach for alopecia.
48 citations
,
October 2010 in “Archives of Dermatological Research” In this study, Juvéderm repeat treatments maintained wrinkle correction in nasolabial folds for up to 21 months and required significantly less filler than the initial treatment, indicating potential benefits for patients.
26 citations
,
December 2020 in “Indian Journal of Plastic Surgery” This review discusses complications from hyaluronic acid filler treatments and explores their causes, presentation, and possible treatment guidelines, without presenting new results.
7 citations
,
October 2023 in “Indian Journal of Plastic Surgery” This study discusses the potential of robots to improve facial aesthetic procedures through enhanced precision and consistency, while noting significant challenges such as high costs and malfunctions that could lead to injuries.
7 citations
,
January 2019 in “Case Reports in Surgery” This case report describes a patient self-injecting facial fillers, highlighting common complications that can mimic oral cancer, leading to diagnostic challenges and economic implications for the National Health Service.
7 citations
,
April 2017 in “Dermatologic surgery” This study concluded that bimatoprost 0.03%, applied either twice or once daily, is safe, well-tolerated, and effective in improving eyebrow fullness and darkness in individuals with eyebrow hypotrichosis.
6 citations
,
January 2018 in “Annals of dermatology/Annals of Dermatology” In this first reported case, a 42-year-old female with Parry Romberg Syndrome was treated using hyaluronic acid filler, which the authors suggest may serve as a safe, simple, and cost-effective alternative to more complex surgical methods.
4 citations
,
May 2023 in “JAAD case reports” This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.
4 citations
,
October 2022 in “Aesthetic surgery journal” This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.
3 citations
,
June 2025 in “Journal of Cosmetic Dermatology” Using combined fat and growth factors can effectively treat hair loss after facial fillers.
3 citations
,
November 2022 in “Facial plastic surgery & aesthetic medicine” In this study, researchers introduced an ultrasound-guided technique for injecting hyaluronic acid fillers into the temple area to enhance safety and precision by visualizing filler placement in the interfascial space.
2 citations
,
August 2023 in “Aesthetic Surgery Journal” This study found that dynamic resilient hyaluronic acid fillers were effective and well-tolerated for correcting moderate-to-severe nasolabial folds in people of color, with improvements in wrinkle severity and fewer adverse events compared to non-people of color.
2 citations
,
June 2016 in “European Journal of Plastic Surgery” This study suggests recommendations for treating and referring patients with severe complications from dermal filler injections, highlighting the need for careful treatment to avoid scarring.
1 citations
,
October 2025 in “Plastic & Reconstructive Surgery Global Open” This study found that a novel cross-linked hyaluronic acid dermal filler is safe and effective for improving lip enhancement, cheekbone augmentation, and nasolabial folds across different skin types, with significant improvements in wrinkle severity and overall facial aesthetics observed.