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Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

Eyebrow transplantation can be successful for Asians with the right technique and care, but regular maintenance is necessary.

Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.

The extracellular matrix affects where tumors can start in the body.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Genes affect cytokine production, which can influence chronic diseases, and certain interventions may help prevent related molecular damage.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.

The nanoparticle-emulsion with polihexanide is more effective and lasts longer for skin antisepsis.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.

The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.

Ginsenoside Rg3 may help hair growth by increasing a growth-related protein in hair cells.

New drugs are improving treatment for hormone-related diseases in small pets.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Arabidopsis collet hairs are good for studying nuclear movement and DNA content increase during growth.

Newer skin resurfacing lasers reduce damage and scarring, with some approved for safe use and minimal side effects.

African-American hair's curl pattern significantly affects its strength and elasticity.

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

Cattle skin has leptin which might control skin and hair growth.

BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.