May 2025 in “The Journal of Rheumatology” This case report describes a 32-year-old Filipino female with mixed connective tissue disease who sequentially developed distinct autoimmune disorders over seven years, highlighting the complexities in diagnosis and management of overlap syndromes.
This research explores if COVID-19, analogous to SARS-CoV, may result in long-term pulmonary fibrosis in recovered patients, although current evidence on the persistence or resolution of lung changes over time remains unknown.
January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
This review explores the association between sleep disturbances, obstructive sleep apnoea, and metabolic consequences like Type 2 diabetes, but reports no new experimental results; the authors elaborate on existing knowledge and suggest complex interconnections with fat accumulation and various syndromes.
May 2017 in “InTech eBooks” This article describes various hair and scalp examination techniques, including noninvasive, semi-invasive, and invasive methods, noting that trichoscopy is a simple, well-accepted, noninvasive technique for evaluating hair loss patients and monitoring treatment.
April 2017 in “Journal of Investigative Dermatology” In this study, deep phenotyping of 68 patients with XPD gene defects successfully separated individuals by clinical diagnosis and survival status, potentially improving diagnosis and prognosis for xeroderma pigmentosum and trichothiodystrophy.
1 citations
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March 2014 in “Turkderm” Trichoscopy helps tell different hair loss types apart using specific scalp and hair patterns.
January 2020 in “Journal of Cutaneous and Aesthetic Surgery” The conference improved skills and knowledge in skin and aesthetic surgery.
April 2012 in “Informa Healthcare eBooks” Alopecia areata is a common autoimmune condition causing varying hair loss, diagnosed by specific patterns of inflammation around hair follicles, with several treatment options available.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
37 citations
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December 2018 in “Frontiers in Immunology” This study found that fibroin/gelatin and spidroin microparticles increased re-epithelialization rates and inhibited scar formation in mouse models of deep skin wounds.
1 citations
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April 2023 in “Science Advances” This study found that sustained ERK activity during tissue regeneration in spiny mice is linked to fibroblast growth factor and ErbB signaling, while inhibiting ERK shifted regeneration toward scarring.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that MAPK/ERK signaling plays a key role in driving tissue regeneration in spiny mice and suggests potential for reversing fibrosis to promote regeneration in mammals.
56 citations
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September 2010 in “Veterinary pathology” This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.
21 citations
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May 2024 in “American Journal of Medical Genetics Part A” This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.
3 citations
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January 2021 in “Medicinski arhiv” In this study, trichoscopic examination revealed that patients with androgenetic alopecia had significantly more yellow dots, pilosebaceous units with one hair, and increased perifollicular hyperpigmentation compared to healthy controls.
1 citations
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January 2022 in “Skin appendage disorders” This review summarizes current knowledge of Dermatitis Cruris Pustulosa et Atrophicans, reports its first known case in Bangladesh and Europe, and highlights the need for more research on its etiology and treatment.
October 2025 in “Preprints.org” This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.
January 2025 in “Indian Journal of Dermatology” This review discusses the various factors implicated in the etiology of frontal fibrosing alopecia and notes the need for effective treatments, reporting no new clinical findings.
December 2024 in “Archiv Euromedica” This review highlights that diagnosing cicatricial alopecia, a hair loss condition linked to several autoimmune diseases, requires trichoscopy and histopathological examination to differentiate it from similar conditions, with early diagnosis being crucial for effective management.
December 2024 in “Journal of Skin and Stem Cell” This review discusses the role of trichoscopy in diagnosing and managing various alopecia types, highlighting its ability to detect specific patterns in both scarring and non-scarring forms, thus aiding in treatment decisions and reducing biopsy necessity.
March 2024 in “Journal of clinical medicine” This study examined trichoscopic findings in androgenetic alopecia, reporting that hair diameter variability, vellus hairs, and the peripilar sign are valuable indicators for diagnosing this condition.
November 2023 in “International Journal of Dermatology” This review presents European expert guidelines for diagnosing androgenetic alopecia across genders but reports no new clinical findings; it emphasizes the importance of trichoscopy for differentiating similar conditions.
17 citations
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August 2020 in “Stem Cell Research & Therapy” In this study, SIRT1-modified human umbilical cord mesenchymal stem cells reduced peritoneal fibrosis in a rodent model, suggesting potential as a treatment strategy for peritoneal dialysis-induced damage.
177 citations
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March 2018 in “International Journal of Molecular Sciences” This review discusses the role of mTOR kinase in pulmonary fibrosis and explores how mTOR inhibitors may help slow the progression of this condition, but it reports no new results.
169 citations
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January 2018 in “Cell Reports” In this study, researchers successfully derived skin organoids from mouse pluripotent stem cells that spontaneously produce hair follicles, potentially aiding in hair growth research and in vitro drug testing.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
13 citations
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October 2021 in “Anais Brasileiros de Dermatologia” This article discusses how dermoscopy, particularly "entomodermoscopy," aids in diagnosing skin infestations and infectious dermatoses, enhancing clinical evaluations, and monitoring treatment efficacy for conditions like scabies, pediculosis, myiasis, and tungiasis.
4 citations
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September 2025 in “Pharmaceutics” This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.