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Osteoma cutis is a rare, benign skin condition where bone forms in the skin.

A rare skin tumor with bone formation was successfully removed without recurrence.

All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.

Fibroblast growth factors are crucial for hair follicle development and regeneration.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Claudin-1 is important for the barrier function and growth of hair.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.