1 citations
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January 2021 This review covers the use of platelet-rich plasma in dermatology for wound healing, hair restoration, skin rejuvenation, and dermal augmentation, and notes the need for standardized guidelines.
1 citations
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December 2019 in “Protetyka Stomatologiczna” This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.
April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
April 2026 in “Stem Cell Research & Therapy” This systematic review reports that regenerative medicine therapies, such as conditioned media, platelet-rich fibrin, and stem cells, show promising efficacy and safety in treating androgenetic alopecia, though heterogeneity in study protocols and limited long-term data emphasize the need for further research to optimize these strategies.
June 2025 in “Journal of medical and dental science research.” This article explores the potential of platelet-rich fibrin therapies for androgenetic alopecia and highlights their possible advantages over traditional treatments without reporting new clinical results.
May 2025 in “Journal of medical and dental science research.” This article discusses the potential role and mechanisms of platelet-rich fibrin therapies in androgenetic alopecia management, exploring their possible benefits over existing treatments but reports no new clinical results.
February 2025 in “Archives of Dermatological Research” In this study, researchers administered injectable platelet-rich fibrin (i-PRF) to 30 patients with androgenetic alopecia, finding an 80% response rate after 6 months, with improved hair density and reduced scalp symptoms, while reporting minimal adverse reactions.
January 2025 in “Annals of dental specialty” This study found that Aloe Vera, injectable platelet-rich fibrin (i-PRF), and their combination affected the proliferation of mesenchymal stem cells derived from human hair follicles, with varying concentrations tested for proliferation and cytotoxic effects.
December 2024 in “Research Journal of Medical Sciences” Injectable Platelet Rich Fibrin effectively improves hair growth in males with hair loss.
December 2024 in “Biological and Clinical Sciences Research Journal” In this study, injectable platelet-rich fibrin (I-PRF) was found to be more effective than platelet-rich plasma (PRP) at improving hair growth outcomes and patient satisfaction for androgenic alopecia.
This review suggests that injectable platelet-rich fibrin therapy shows promise for improving hair density in androgenetic alopecia and enhancing facial skin texture and elasticity, but larger studies are needed to confirm its effectiveness.
October 2023 in “European journal of dermatology/EJD. European journal of dermatology” In this study, I-PRF, a blood-derived biomaterial without anticoagulants, was found to inhibit melanin production and reduce oxidative stress damage in a rat model of melasma, suggesting it as a safe and cost-effective treatment option.
June 2023 in “Journal of Face Aesthetics” This review discusses the potential role of platelet-rich fibrin in aesthetic and dental procedures but highlights the need for more rigorous future studies to confirm its effectiveness and safety.
November 2022 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” Platelet-rich fibrin speeds up burn wound healing in rabbits.
September 2022 in “British Dental Journal” Platelet-rich fibrin is becoming popular for medical and cosmetic uses like hair growth and natural fillers.
January 2021 in “Hair therapy & transplantation” This study reports encouraging results in treating androgenetic alopecia by combining injectable PRF and PDO thread insertion on the scalp.
June 2022 in “International Journal of Research in Dermatology” This study found that injectable platelet-rich fibrin significantly improved hair growth and patient satisfaction as a cost-effective adjuvant treatment for androgenetic alopecia.
November 2021 in “Journal of Aesthetic Nursing” This study found that injectable platelet-rich fibrin (iPRF) combined with microneedling is a safe and effective treatment for male androgenetic alopecia, but it currently lacks comparison data against other popular therapies.
28 citations
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September 2023 in “International Journal of Biological Macromolecules” Animal experiments in this study demonstrated that a new sandwich-like fiber/sponge dressing design, which enhances wound healing through improved moisture management and faster exudate evaporation, resulted in more significant wound size reduction compared to commercial and control dressings.
July 2026 in “Advanced Healthcare Materials” This review discusses the potential of silk fibroin-based injectable hydrogels as next-generation biomaterials for regenerative medicine, exploring their therapeutic advantages, challenges, and future clinical applications.
This study found that an injectable hydrogel, SF-g-SDA, outperformed commercial Tegaderm™ in healing wounds, promoting collagen deposition, and enhancing neovascularization in animal models.
3 citations
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February 2023 in “Journal of drug delivery science and technology” In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.
August 2026 in “Materials Technology” This study developed a multifunctional TA-MoS2-SF hydrogel for diabetic ulcer treatment, demonstrating enhanced photothermal bactericidal effects, immune environment remodeling, and fibroblast proliferation, suggesting it may serve as an effective 'antibacterial-immunomodulatory-repair' strategy.
2 citations
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September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study investigated various animal tissues from adult mice and embryonic chicks, finding that tissue stiffness follows a sub-linear power law relationship with Collagen-I levels, consistent with cellularized collagen gels but not acellular ones.
January 2023 in “Advanced Biology” This study observed that DNA methylation dynamics, including global hypermethylation and site-specific changes, influenced gene expression associated with immune activation and PI3K-Akt signaling during esophageal tissue regeneration with acellular grafts.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” This study found that a unique transglutaminase in guinea pig hair-follicles, distinct from liver transglutaminase, likely plays a role in forming protein cross-links via ε(γ-glutamyl)lysine bonds.
51 citations
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May 1984 in “Journal of the American Academy of Dermatology” In this study, the authors observed that cell-mediated immune mechanisms may be involved in the pathogenesis of benign follicular mucinosis, based on the cellular and immunological characteristics of two patient cases.
41 citations
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October 2024 in “Nature Communications” In this study, researchers developed a wearable red and blue LED patch and a sprayable fibrin gel to treat infected wounds at home, demonstrating effective infection control and enhanced wound healing in diabetic mice and minipigs.
34 citations
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August 1966 in “Experimental cell research” This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
15 citations
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July 2022 in “Biomedicines” This study found that bioengineered skin substitutes developed for 21 or 28 days effectively mimic native skin's ability to absorb UV radiation, suggesting suitability for treating severe skin defects.