39 citations,
April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
2 citations,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
24 citations,
January 2006 in “Dermatologic clinics” Hair sunscreens are important for maintaining hair's cosmetic value.
13 citations,
January 2016 in “Burns & Trauma” Vacuum massage may improve skin elasticity and induce changes in skin cells, but evidence for treating burn scars is insufficient and more research is needed.
5 citations,
February 2016 in “Genetic Testing and Molecular Biomarkers” Hair loss is significantly linked to lower levels of certain genes in hair follicles.
1 citations,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
April 2016 in “Proceedings of SPIE” UV-induced autofluorescence is effective for identifying different types of alopecia.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
47 citations,
November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
20 citations,
February 2019 in “Genes” The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
16 citations,
July 2020 in “Advanced functional materials” 3D cell-derived matrices improve tissue regeneration and disease modeling.
10 citations,
January 2016 in “Elsevier eBooks” Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
2 citations,
July 2017 in “IEEE Photonics Journal” The study found that combining SHG and OCT effectively monitors skin wound healing in mice.
1 citations,
June 2019 in “Food Research” Tempeh oil rich in linoleic acid may protect against skin aging caused by UV light.
1 citations,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
1 citations,
November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
160 citations,
April 2012 in “Journal of Cellular and Molecular Medicine” Telocytes might help with skin repair and regeneration.
150 citations,
June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
97 citations,
May 2008 in “Journal of Cutaneous Pathology” Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.
89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
83 citations,
June 2020 in “Materials & Design” Sponge helps heal wounds faster with less inflammation and better skin/hair growth.
76 citations,
May 2007 in “Menopause International” After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
52 citations,
January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
50 citations,
November 2010 in “Otolaryngologic Clinics of North America” Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.