13 citations
,
January 2017 in “Cosmetics” This review discusses in vitro methods for evaluating the effects of hair care products on hair fibers, reporting no new results; the authors emphasize the importance of selecting appropriate and accurate equipment for testing.
10 citations
,
May 2019 in “International Journal of Environmental Research and Public Health” This study found that finasteride treatment in male rats altered steroid hormone homeostasis and caused kidney damage, suggesting potential risks for patients with renal dysfunction on androgen or antiandrogen therapy.
5 citations
,
November 2017 in “Asian Journal of Beauty and Cosmetology” This study found that sinapic acid demonstrated antioxidant and anti-inflammatory effects against UVB-induced damage in human keratinocytes, suggesting its potential as an anti-aging cosmetic ingredient.
11 citations
,
October 2019 in “Cancers” This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.
4 citations
,
May 2019 in “Biology open” This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.
May 2024 in “Indian journal of pharmacy and pharmacology” This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.
40 citations
,
May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.
20 citations
,
January 2003 in “Journal of oleo science” This study found that both everyday physical and environmental stresses, as well as chemical treatments, contributed to hair damage, with cuticle layers being more noticeably affected.
11 citations
,
July 2021 in “Sustainability” In this study, researchers found that replacing natural aggregates with animal bones and human hair with increased microroughness may improve the mechanical strength and durability of concrete.
36 citations
,
October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
8 citations
,
June 2021 in “International Journal of Molecular Sciences” In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
10 citations
,
May 2012 in “PloS one” This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.
February 2025 in “International Journal of Cosmetic Science” This research studied European human hair, finding that cysteic acid and protein carbonylation increased with both chemical and photochemical oxidation. Protein carbonylation was highlighted as a more sensitive marker for photochemical oxidation, providing better in situ visualization of hair damage than cysteic acid.
July 2025 in “Journal of Cosmetic Dermatology” This study established a model of heat-damaged hair to assess hair care products, finding that daily hair drying for a month causes notable cuticle lifting, reduced mechanical properties, and increased protein release, and the model simulates even more severe damage.
43 citations
,
September 2006 in “Annals of Plastic Surgery” This article presents a unique case of hair-thread tourniquet syndrome in a 3-month-old, with a hair causing bony erosion of the toe, and includes a literature review and meta-analysis.
24 citations
,
October 2008 in “PubMed” This article discusses how UV radiation affects hair protein and pigment, destructuralizes keratin, and emphasizes the protective role of melanin, but reports no new clinical results.
4 citations
,
June 2019 in “International Journal of Cosmetic Science” This study developed mathematical models showing that heat penetrates individual hair quickly but takes longer to reach the center of hair bundles, helping understand potential damage from high-temperature styling tools.
4 citations
,
August 2016 in “PubMed” This study analyzed how oxidative hair dye leaches from pigmented and nonpigmented hair during wash cycles, finding that melanin influences the dye deposition and leaching processes.
3 citations
,
July 2003 in “PubMed” This study found that laser-based goniophotometry can effectively monitor changes in hair surface reflection related to color and cuticle cell tilt across different ethnic origins.
2 citations
,
January 2004 in “PubMed” This study concluded that Polyquaternium-10 conditioner softens the surface of the scale face on hair fibers.
1 citations
,
November 2022 in “Molecules/Molecules online/Molecules annual” This study found that low-molecular-weight hyaluronate significantly improved the mechanical strength and elastic modulus of overbleached hair by enhancing hydrogen bond networks within keratin.
July 2025 in “Scientific Reports” This study reported that fermented grapeseed oil may enhance hair permeability and improve strength and color retention in chemically treated hair compared to regular grapeseed or silicone oils.
This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.
24 citations
,
November 2015 in “International Journal of Cosmetic Science” This study demonstrated that oxidative stress contributes to dandruff, and using a potentiated ZPT shampoo improves scalp and hair condition by reducing oxidative stress.
14 citations
,
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
6 citations
,
May 2004 in “Dermatologic Surgery” This article discusses various techniques to achieve a cosmetically attractive single donor scar in hair restoration surgery, reporting no new clinical findings.
5 citations
,
September 2022 in “Antioxidants” This study found that the clionasterol-rich hexane fraction of Caulerpa racemosa may protect against particulate matter-induced skin damage by reducing oxidative stress and mitochondrial-mediated apoptosis in human keratinocytes and zebrafish.
1 citations
,
June 2016 in “Experimental Dermatology” This article discusses advancements in proteomic and metabolomic analysis techniques for studying hair damage but provides no new clinical results; the authors express interest in applying metabolomics to develop strategies for reducing hair damage from chemical treatments.
34 citations
,
January 2011 in “Annals of dermatology/Annals of Dermatology” This study found that using a hair dryer at 15 cm with continuous motion causes less surface damage to hair compared to natural drying, although higher temperatures increased overall surface damage.
16 citations
,
October 2015 in “Photochemistry and photobiology” This study found that higher concentrations of copper (II) ions in human hair increase protein oxidative modification, contributing to hair damage regardless of UV exposure and pigmentation level.