April 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study compared the effects of direct heat perms and softening heat perms on hair, analyzing damage and morphological changes to understand their impact on hair fibers and provide foundational data for future research.
This study found that anti-keratin antibody from immunized cow milk increases the resistance of damaged hair to stretching and inhibits fracture from excessive brushing.
21 citations
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March 2015 in “Journal of The American Academy of Dermatology” In this study, five out of six patients treated with vemurafenib for metastatic melanoma experienced hair loss, which improved after topical steroid treatment.
15 citations
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February 2017 in “International Journal of Women's Dermatology” This source summarizes discussions by an advisory board of twelve experts on hair loss, focusing on heredity, aging, and environmental impacts, and emphasizing strategies that may slow alopecia.
115 citations
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November 2004 in “Brain Behavior and Immunity” This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.
22 citations
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July 2004 in “International Journal of Cosmetic Science” This article reviews the impact of UV radiation and visible light on human hair structure and summarizes protective strategies, reporting no new clinical results.
20 citations
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July 2010 in “Skin Research and Technology” This study found that aging in Korean individuals is associated with changes in hair diameter and surface structure, as observed through atomic force microscopy.
January 2026 in “International Journal of Biological Macromolecules” This study found that different polypeptides, including KP peptide and hydrolyzed keratin, can improve the mechanical properties of damaged hair under varying conditions, with reduction environments and cysteine content influencing their effectiveness.
April 2023 in “CRC Press eBooks” This research highlights the key interactions of hair cosmeceuticals, focusing on their effects on the hair fiber surface, cuticle, and cortex, which are crucial for protection and mechanical strength, particularly in damaged hair.
1 citations
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January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
September 2025 in “International Journal of Cosmetic Science” This study found that a 0.5% cationic guar gum and 0.5% anionic surfactant formulation formed stable coacervates with improved adhesion and coverage on damaged hair, suggesting it may enhance the effectiveness of hair conditioning products compared to other ratios.
14 citations
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January 1996 in “Journal of Forensic Sciences” This in vitro study found that opiate diffusion was more pronounced in damaged hair fibers than in undamaged ones, with high opiate concentrations detected in fiber centerpieces.
23 citations
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August 2019 in “Proceedings of the National Academy of Sciences of the United States of America” Pollution exposure speeds up hair damage.
7 citations
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February 1985 in “Textile Research Journal” This study found that wool fiber surfaces damaged in processing tended to have cellular debris adhering to them, while undamaged surfaces did not show this interaction.
1 citations
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July 2019 in “Microscopy Today” This source highlights the utility of cationic polymers in haircare products for protecting against hair damage from chemical treatments and grooming, and describes how microfluorometry can measure polymer deposition and penetration on hair fibers.
20 citations
,
December 2012 in “Journal of molecular structure” This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.
16 citations
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October 2003 in “Journal of applied polymer science” This study found that chemically modifying hair with 2-iminothiorane hydrochloride improved the permanence of hair setting without damaging the hair by increasing disulfide bonds.
6 citations
,
November 2017 in “Journal of the Peripheral Nervous System” This study found that mercury chloride administration in rats led to decreased intraepidermal nerve fibers and increased Langerhans cells, suggesting small nerve fiber damage after mercury poisoning.
May 2026 in “Advanced Materials Interfaces” This study reported that a new coating made with delaminated Ti₃C₂ MXene nano-sheets and a tea-derived compound effectively protects hair keratin from damage by providing UV screening, thermal dissipation, and antioxidation, while also enhancing mechanical strength and restoring wettability.
September 2024 in “Heliyon” In this study, researchers observed that even a single session of hair dyeing can damage hair fibers, with significant worsening of mechanical properties and protein composition after three or more consecutive treatments, emphasizing the need to consider the cumulative impacts of dyeing on hair health.
This study found that a bio-based repair solution containing hydrolysed wool keratin, serine, and transglutaminase improved the physical and chemical properties of damaged hair, increasing its strength, flexibility, and thermal stability while offering long-lasting protection against chemical damage.
2 citations
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July 2012 in “PubMed” In this study, the use of internal wool lipid liposomes was shown to improve the lipid composition and increase the resistance to breaking in both untreated and chemically treated hair fibers.
October 2021 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that applying a cosmetic active ingredient improved the Young's modulus of chemically damaged human hair fibers, suggesting enhanced mechanical properties compared to untreated fibers.
February 2025 in “Brazilian Journal of Hair Health” This study reports that the candle flame technique "velaterapia," popular in Brazil for addressing split ends, can damage hair fibers due to bubble formation at high temperatures, despite thermal protectors providing some cuticle protection.
35 citations
,
February 2006 in “Textile Research Journal” This study found that xylanase and pectinase enzymes clean wool and specialty hair fibers as effectively as soap, without causing physical damage, whereas resinase was not effective.
3 citations
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June 2019 in “Journal of cosmetic dermatology” In this study, tresses treated with pH 1.0 acid straightener showed better straightening but more damage to hair properties compared to those treated with pH 2.0.
July 2026 in “Scientific Reports” This study found that wool felting in Ukrainian Carpathian Mountain sheep is linked to significant changes in fatty acid composition, particularly highlighting a decrease in 18-methyleicosanoic acid in bound lipids, suggesting it as a potential marker for cuticle lipid layer damage during felting.
10 citations
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March 2005 in “International Journal of Cosmetic Science” This study found that photochemical and cosmetic chemical oxidation of hair causes surface damage by delipidation and acid formation, which can be characterized and quantified using microfluorometry and X-ray photoelectron spectroscopy.
1 citations
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January 2006 This study found that keratin fibers like human hair undergo thermal and mechanical transitions that can help assess changes from cosmetic processes such as bleaching and perm-waving.
3 citations
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January 2002 in “Springer eBooks” This study found that using cationic and non-ionic polymers during alkaline hair relaxer treatments may help strengthen hair and control swelling, potentially reducing damage.