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The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Epigenetic changes are crucial for hair follicle stem cells to function properly.

Impaired autophagy may cause hair loss by triggering early catagen.

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

Researchers found four genes that could help diagnose severe alopecia areata early.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Wnt5a may slow down hair growth in mice.

Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.

The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.

CD4+ skin cells may be precursors to basal cell carcinoma.

Muse cells keep their special features and can become different cell types even after being frozen and thawed three times.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

Hair follicle stem cells help skin heal and grow during stretching.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

The skin microbiome helps heal wounds and can be targeted to improve healing.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.