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Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

PCOS requires personalized treatment to improve life quality and reduce health risks.

EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.

Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.

Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.

Minoxidil is effective for hair growth and safe for long-term use.

The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.

The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.

New treatments for skin and hair repair show promise, but further improvements are needed.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.