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Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.

Healthy diet and exercise are important for women with PCOS to manage weight and metabolic issues, and supplements like omega-3, vitamin D, and inositol may help.

Proper nutrition can help manage PCOS symptoms and improve overall health.

Health coaching helped reduce waist size, increase physical activity, and improve lifestyle in overweight women with PCOS.

Uterine transplants for transgender women are feasible but need more research.

Aging slows wound healing due to weaker cells and immune response.

Physical inactivity is a primary cause of many human illnesses.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Polycystic Ovary Syndrome (PCOS) affects Iranian women's feelings of femininity and self-image.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

Auriculotherapy and Aslagh capsules are as effective as metformin for treating PCOS symptoms, with auriculotherapy slightly better for reducing hair growth.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

Understanding Polycystic Ovary Syndrome (PCOS) and its causes can lead to effective treatments.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.