October 2024 in “Andrology” This study investigated paternal drug exposure using FDA data and identified significant associations with reproductive health risks, including congenital anomalies linked to immunosuppressive drugs, and emphasized specific risk combinations like biologics and abortion, diazepam and small for date baby, and finasteride and cryptorchidism.
This study conducted a systematic review and meta-analysis but did not report results, aiming to clarify the unclear association between female pattern hair loss and polycystic ovary syndrome, along with potential links to altered fertility factors.
January 2022 in “Skin appendage disorders” The researchers concluded that while oral finasteride is effective and generally safe for treating male pattern hair loss, careful patient selection and risk assessment are important to address potential concerns such as fertility issues and mental health risks.
22 citations
,
October 2017 in “Australian & New Zealand Journal of Obstetrics & Gynaecology” This study found that the prevalence of PCOS among Australian women aged 16-29 was 12% using NIH criteria, with fertility concerns being the most distressing aspect for those diagnosed.
April 2026 in “NSUWorks (Nova Southeastern University)” This review concludes that creatine monohydrate is a safe and effective supplement, offering potential health benefits beyond athletic performance; however, it addresses concerns regarding its use among specific populations and effects on various health aspects.
26 citations
,
March 2001 in “PubMed” This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
1 citations
,
August 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” BMI should be considered in future research on dutasteride's effects on fertility.
33 citations
,
January 2009 in “Journal of Cutaneous and Aesthetic Surgery” This study found no clear evidence that finasteride negatively affects erectile function, though it does cause a reduction in ejaculatory volume and has potential implications for prostate cancer risk.
47 citations
,
January 2021 in “Fertility and Sterility” This review assesses the current literature on COVID-19's effects on male sexual and reproductive health, highlighting significant research gaps and providing guidance for patient counseling.
9 citations
,
March 2021 in “Hormones” This review discusses how COVID-19 may affect gonadal function and potential gender differences, but reports no clinical results; it highlights possible mechanisms and new treatment approaches from recent literature.
45 citations
,
March 2015 in “Clinical Endocrinology” This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.
19 citations
,
April 2020 in “Dermatologic Therapy” This review found that dutasteride is more potent than finasteride as a dual receptor dihydrotestosterone blocker for treating androgenetic alopecia and shares a similar safety profile in terms of fertility, teratogenicity, neurotoxicity, and hepatotoxicity.
222 citations
,
January 2014 in “International journal of reproductive medicine” This paper reviews the complex pathophysiology of polycystic ovary syndrome, exploring how hormonal and metabolic disturbances contribute to its symptoms and related health risks, but it presents no new findings.
March 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” This study found that long-term use of dutasteride in men taking it for androgenetic alopecia may lead to persistent decreases in semen volume and sperm motility, potentially impacting fertility, with significant impairment observed after 17.8 to 20.3 months of treatment.
January 2026 in “Scholars Journal of Medical Case Reports” This article outlines a diagnostic and treatment approach for polycystic ovarian syndrome in young women, emphasizing lifestyle modifications, hormonal treatments, and specialist referrals for managing symptoms and fertility concerns.
December 2025 in “Insights-Journal of Health and Rehabilitation” This study assessed the impact of Polycystic Ovarian Syndrome on married women's quality of life, finding significant negative effects on psychological well-being, fertility-related concerns, and body image, underscoring the need for comprehensive and culturally sensitive interventions.
1514 citations
,
December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
29 citations
,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses factors affecting fertility in both men and women with congenital adrenal hyperplasia and emphasizes individualized preconception management but reports no new clinical results.
May 2019 in “Paediatrics and child health” This review discusses diagnosis and management strategies for polycystic ovary syndrome in teenagers and reports no new clinical findings, emphasizing tailored approaches considering symptoms, psychological well-being, and fertility needs.
18 citations
,
February 2016 in “The Journal of Clinical Endocrinology and Metabolism” This article reviews emerging opportunities and challenges in male reproductive medicine, including advancements and unmet needs in erectile dysfunction, androgen deficiency, and fertility, but reports no new clinical findings.
1 citations
,
November 2005 in “Journal of Andrology” This meeting abstract details various lectures and workshops from the 30th Annual Meeting of the American Society of Andrology, including findings on genetic and physiological factors affecting male fertility, but reports no new clinical results.
This review addresses various gender-specific challenges in managing women with epilepsy, such as AED-related cosmetic concerns and hormonal impacts on seizure frequency, but it reports no new clinical findings.
This article reviews the contraceptive agent Depo-Provera, discussing its effectiveness, potential side effects, and safety concerns, but reports no new clinical results.
28 citations
,
January 2017 in “Obstetrician & gynaecologist/The obstetrician & gynaecologist” This article discusses the complexities of diagnosing and managing polycystic ovary syndrome, highlighting the challenges related to fertility treatment criteria, insulin resistance, and long-term health implications, but reports no new clinical findings.
This study investigated the epigenetic effects of finasteride on reproductive signaling pathways using Sertoli cell models and found that finasteride exposure led to altered epigenetic profiles in multiple genes, including ESR1 and DNMT3A, indicating potential impacts on reproductive-related pathways.
May 2025 in “International Journal of Innovations in Science Engineering and Management.” This study reviewed the literature on cryptorchidism in dogs and found it may be associated with dermatological issues like alopecia, with surgical intervention and cyclosporine offering partial benefit.
In this study, three cases of young men using finasteride for five years showed altered sperm morphology and motility issues, with partial improvement observed after discontinuation.
This review discusses the diagnostic criteria and management challenges for polycystic ovarian syndrome and reports no clinical results, highlighting complications associated with pregnancy in women with the condition.
The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.