January 2018 in “Journal of Crohn s and Colitis” This study found that high-dose intravenous ferric carboxymaltose may reduce inflammatory activity in patients with inflammatory bowel disease and iron deficiency anaemia, as evidenced by decreased CRP levels and improved clinical disease indices.
4 citations
,
January 2012 in “Human health handbooks” This study suggests that ferrous ferric chloride plays a role in regulating skin homeostasis by promoting the proliferation and differentiation of skin cells from a distance.
4 citations
,
January 2002 in “Indian Journal of Pharmaceutical Sciences” This study developed a precise and reproducible method for estimating finasteride in tablet formulations using a colorimetric reaction with specific reagents.
4 citations
,
January 2016 in “Annals of dermatology/Annals of Dermatology” Iron supplements can restore normal hair color in cases of premature graying linked to iron deficiency.
20 citations
,
May 2023 in “Biological Trace Element Research” This study found that repeated oral intake of 0.5 or 5 mg/kg of cobalt ferrite nanoparticles induced pulmonary toxicity in rats, with dose-dependent oxidative stress and inflammation observed, but no notable toxicity was seen at a 0.05 mg/kg dose.
This study suggests that raising the lower normal serum ferritin level to 50 ng/mL may improve organ functions even when hemoglobin levels are normal.
February 2013 in “Journal of the American Academy of Dermatology” Iron supplements may reverse premature hair graying caused by iron deficiency.
August 2026 in “International Journal For Multidisciplinary Research” This study evaluated a 90-day oral iron supplementation regimen in adults with moderate to severe iron deficiency anemia, finding significant hematological improvements, symptom resolution, and good tolerability, supporting its effectiveness as a nutritional approach for managing this condition.
April 2023 in “Tikrit Journal of Pharmaceutical Sciences” In this study, researchers assessed the effects of deferasirox in 85 children with ß-thalassemia in Kirkuk and reported that while 55.3% experienced a reduction in serum ferritin, 9.4% had adverse effects, indicating that deferasirox is generally well-tolerated as an iron chelator with modifiable side effects.
53 citations
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November 2021 in “Molecular Human Reproduction” This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.
47 citations
,
November 2010 in “Vox Sanguinis” This study found that a targeted iron supplementation program prevented anemia and improved blood return rates among premenopausal female blood donors with iron deficiency.
October 2023 in “Siriraj Medical Journal” This study found that oral iron supplementation, when given with topical 3% minoxidil, does not outperform the use of topical 3% minoxidil alone in treating female pattern hair loss and iron deficiency.
This study investigated the safety and efficacy of IV iron maltoside 1000 in treating iron-deficiency anemia among children with IBD and found a significant increase in hemoglobin levels by 6 weeks, maintained for up to a year, with minimal side effects reported.
14 citations
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January 2020 in “Women's health reports” This study found that iron therapy improved nonhematological symptoms and cognitive function in women with iron deficiency anemia, highlighting the need for attention to these symptoms in improving quality of life.
March 2023 in “International Journal of Science and Research (IJSR)” This article discusses iron deficiency anemia, its health implications, and the effectiveness of oral iron supplements in treatment, but reports no new clinical findings.
4 citations
,
March 2023 in “Molecules/Molecules online/Molecules annual” This study successfully extracted gallic acid and ferulic acid using a biocompatible aqueous two-phase system, suggesting a sustainable approach for producing antioxidants as food supplements for hair health.
This study found that while iron supplements are generally well tolerated by patients with anemia, their clinical benefit in those without iron deficiency is modest.
7 citations
,
January 2009 in “Journal of Pharmacy Research” This study found that fractions of Tridax procumbens extract demonstrated significant antioxidant activity, comparable to standard ascorbic acid, in laboratory tests.
10 citations
,
November 2021 in “European Journal of Clinical Nutrition” In this study, non-anemic menstruating women with iron deficiency showed significant associations with symptoms such as recent hair loss at serum ferritin levels ≤ 20 µg/l and restless legs syndrome at levels ≤ 50 µg/l.
January 2015 in “Iraqi Journal of Hematology” In this study, oral iron replacement therapy showed improvement in hair loss severity for some women with low serum ferritin levels, but not all responded.
2 citations
,
February 2004 in “Biopolymers” This study found that 4-(4-Phenoxybenzoyl)benzoic acid derivatives may act as antioxidants by scavenging certain reactive oxygen species but exhibit prooxidant behavior under specific conditions.
This study found that women with nonscarring alopecia had significantly lower ferritin levels compared to women without the condition.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
10 citations
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January 2025 in “Frontiers in Nutrition” This review discusses the potential role of the dietary antioxidant index in reducing the risk of various diseases, including obesity-related conditions, certain cancers, osteoporosis, and mental illnesses, but calls for further studies to confirm these findings.
22 citations
,
June 2001 in “International Journal of Cosmetic Science” This review discusses the role of iron from cosmetic sources in skin nutrition and reports no clinical results, highlighting its significance for skin, hair, and nail health.
March 2025 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” In this study, the researchers observed that ferulic acid and resveratrol effectively protected chemically treated hair from oxidative damage, particularly against protein loss and color degradation, but not cisteine oxydation prevention, and these antioxidants also offered protection against sun-induced damage when used in conditioners.
8 citations
,
November 2019 in “Journal of Trace Elements in Medicine and Biology” Higher hair iron levels are linked to changes in brain structure and function.
4 citations
,
October 2020 in “Toxicology Mechanisms and Methods” This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
5 citations
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August 2020 in “Advances in Hematology” In this study, an intervention to automatically measure ferritin detected iron deficiency in about 28% of women with alopecia, potentially helping to address hair loss.
This study, conducted in Indramayu, Indonesia, reported that iron supplementation significantly increased hemoglobin levels in infants, while zinc supplementation reduced persistent diarrhea risk but increased susceptibility to runny nose and measles; complex interactions with diet warrant further investigation.