April 2026 in “Dove Medical Press (Taylor and Francis Group)” This study found that Myrtus communis leaf extract significantly decreased IL-1α and increased VEGF gene expressions in human keratinocytes, which may relate to the plant's traditional uses for hair loss and wound healing, though further research is needed to explore these effects.
January 2019 in “International Journal of Plant Animal and Environmental Sciences” This study found that a 50% ethanol extract from marine green alga Chlamydomonas sp. W80 exhibited several bioactive properties, including skin lightening and hair growth promotion effects, with potential implications for bioenergy and high-value coproducts.
July 2004 in “Clinics in Dermatology” This research introduced and validated the Scales of General Well-Being, which reliably measures overall and specific aspects of well-being across different demographics in North America.
8 citations
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June 2022 in “Cosmetics” This study found that coffee berry extract demonstrated anti-aging properties in skin and hair cells, showing significant anti-collagenase activity and stimulating hair-related gene expression, suggesting its potential for use in cosmeceuticals.
December 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that polysaccharide extracts from ginseng, green tea, shiitake, and aloe vera effectively protected human follicle dermal papilla and keratinocyte cells by promoting cell proliferation or inhibiting apoptosis, suggesting potential for these extracts as ingredients in cosmetics or pharmaceuticals to prevent hair loss.
22 citations
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November 2024 in “Planta” This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
14 citations
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April 2021 in “Heliyon” This study found that both alcoholic and aqueous extracts of Punica granatum L. showed potential for promoting hair growth and exhibited anti-lice and antidandruff activities in a mouse model.
7 citations
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December 2022 in “Plants” This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.
7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
4 citations
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November 2022 in “Nutrients” In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.
3 citations
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January 2023 in “Agronomy” This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.
2 citations
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May 2023 in “Plants” In this study, Allium hookeri extract increased viability and size of dermal papilla cell spheroids and reduced oxidative stress effects, potentially promoting hair growth by regulating specific protein signaling pathways in human cells.
January 2026 in “Environmental Science and Pollution Research” In this study, oral administration of wheat sprout extract significantly protected rats against skin damage caused by acrylamide exposure by enhancing antioxidant defenses, reducing oxidative stress, and preserving skin structure, highlighting its potential as a sustainable protective agent against environmental skin toxins.
November 2025 in “Frontiers in Pharmacology” This mini-review examines ethnopharmacological approaches to manage hair loss in postmenopausal women, highlighting promising botanical remedies like saw palmetto, rosemary oil, and ginseng. The authors underscore a need for more interdisciplinary trials and focus on traditional remedies' multifaceted benefits, while noting gaps in menopausal-specific evidence.
March 2025 in “Journal of Cosmetic Dermatology” This study explored the effects of TTFE on male androgenic alopecia, finding that topical application increased hair density, follicular diameter, and scalp hydration while reducing water loss and sebum production in a 12-week trial.
December 2024 in “Food Bioscience” In a depilation mouse model, this study found that Limosilactobacillus fermentum MF10 promoted hair growth and increased follicle size by activating skin Wnt/β-catenin signaling and modulating gut microbiota, with effects comparable to the positive control finasteride.
July 2024 in “International Journal of Molecular Sciences” In this study, Nigella sativa oil was found to promote dermal papilla cell proliferation and may reduce oxidative stress, suggesting its potential as a hair loss intervention.
November 2021 in “Journal of pharmaceutical research international” This review examines the benefits and preparation methods of herbal versus chemical depilatories, highlighting the potential safety and efficacy advantages of herbal ingredients but provides no new experimental findings.
July 2019 in “Technology audit and production reserves” This research discusses the formulation of probiotic gel shampoos with whey peptides and plant extracts, highlighting their potential effectiveness and market feasibility in Ukraine.
17 citations
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June 2022 in “Frontiers in Nutrition” This study found that fermented Flammulina velutipes polysaccharides showed higher antioxidant and anti-inflammatory capacities than non-fermented ones, suggesting potential use in functional foods and health products.
November 2025 in “Journal of Microbiology and Biotechnology” This study demonstrates that pea sprout extract promotes hair growth by activating specific signaling pathways and providing antioxidant and anti-inflammatory effects, suggesting its potential as a natural alopecia treatment.
This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.
9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
March 2025 in “Molecules” This study found that Kyoh®, a flavonol-rich extract from rocket leaves, may promote hair growth by enhancing the expression of hair growth-related genes in laboratory conditions.
January 2025 in “Cosmetics” In this study, the researchers found that Astragalus sinicus extracts improved wound healing, reduced oxidative stress, and activated crucial signaling pathways in dermal papilla cells damaged by dihydrotestosterone, suggesting it may be a promising ingredient for hair loss treatment.
December 2024 in “Biomedical & Pharmacology Journal” In this study, researchers developed and assessed two polyherbal hair tonic formulations, finding that Hair Tonic A containing 10% white tea extract improved hair thickness, manageability, and anti-frizz properties, particularly for blonde and black hair, while demonstrating greater stability compared to Hair Tonic B.
13 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
March 2025 in “Regenerative Therapy” This study suggests that SACM may enhance hair growth more effectively than non-treated ACM, highlighting the potential of S. maxima as a promising agent for use in pharmaceutical and cosmeceutical industries.
August 2023 in “Processes” This study found that fermenting Dendrobium officinale with Lactiplantibacillus plantarum CCFM8661 and other strains increased polysaccharide yields and skin care activity, particularly with CCFM8631, which showed significant improvements in skin cell protection and inflammation reduction in both cell cultures and mouse models.