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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Metabolic syndrome linked to urinary symptoms; hair loss not significant.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Some women with PCOS have rare genetic variants linked to the condition.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

New genes and pathways are important for testosterone production and male sexual development.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Adrenal disorders can cause lasting brain and behavior issues in children.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Most women lack knowledge about androgens and their excess symptoms.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.