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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Innovative methods are reducing animal testing and improving biomedical research.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

Primary cilia affect the size and oil production of eye glands but not the oil's makeup.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Whale genes show changes that help them live in water, like less hair and better flippers.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Quick treatment of hair disorders in teenage girls is important because of the emotional effects.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Recognizing specific features of African-American hair can help diagnose hair loss conditions.

The DNA convention was a valuable opportunity for learning and networking, especially after COVID-19.