15 citations,
January 2022 in “Immune Network/Immune network” New targeted immunotherapies are improving treatment for inflammatory skin diseases.
15 citations,
November 2020 in “Physiological reports” Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.
13 citations,
September 2014 in “Journal of photochemistry and photobiology. B, Biology” UV radiation increases protein loss from hair and reduces hair protein quality.
12 citations,
January 2015 in “Skin appendage disorders” Dermoscopy helps quickly identify hair breakage in people of African descent.
10 citations,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
10 citations,
August 2013 in “Experimental Dermatology” The study revealed a negative regulatory loop between the Hairless (HR) protein and the polyamine putrescine in the epidermis, impacting hair follicle cycling and epidermal homeostasis. HR regulated ornithine decarboxylase (ODC) expression through MYC superfamily proteins, while elevated putrescine levels decreased HR expression. This mutual regulation was linked to hair loss phenotypes in mouse models with altered HR or polyamine enzyme expression. The research suggested that putrescine influenced gene expression through various pathways, including epigenetic mechanisms, affecting a small number of genes in keratinocytes. These findings highlighted the complex regulatory mechanisms involving HR and polyamines, with implications for hair cycling and potentially carcinogenesis.
8 citations,
July 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Curly hair is mechanically different from straight hair and may need new testing methods.
6 citations,
August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
6 citations,
May 2022 in “Frontiers in Microbiology” Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.
6 citations,
January 2016 in “International journal of trichology” Children's hair is more elastic, but tensile strength is similar across different factors.
5 citations,
January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
4 citations,
January 2023 in “Frontiers in Medicine” Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.
4 citations,
June 2022 in “Journal of cleaner production” New eco-friendly method strengthens and sets hair using light and causes less damage.
4 citations,
January 2017 in “International journal of trichology” Castor oil can cause severe hair matting.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
3 citations,
September 2021 in “Data in brief” Bleaching hair changes its structure and weakens it, which is important for understanding hair damage and creating treatments.
3 citations,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
3 citations,
June 2008 in “Springer eBooks” Hair care products clean, protect, style, color, and change hair structure.
2 citations,
October 2023 in “Biology” Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
2 citations,
July 2023 in “Cosmetics” Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.
2 citations,
June 2023 in “Pharmaceutics” Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
1 citations,
March 2024 in “Skin research and technology” A new AI model diagnoses hair and scalp disorders with 92% accuracy, better than previous models.
1 citations,
November 2023 in “Polymers” Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
1 citations,
August 2023 in “Advanced Drug Delivery Reviews” Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
1 citations,
June 2023 in “Genes” Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
1 citations,
January 2018 in “Journal of microscopy and ultrastructure” The method can identify minerals in hair from water, and using coconut oil or conditioner can prevent mineral buildup.
November 2024 in “Medicina” Recognizing scalp symptoms in PRP is crucial for proper diagnosis and treatment.
November 2024 in “Nanomaterials” The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.
October 2024 in “International Journal of Molecular Sciences” Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
October 2024 in “Dermatologica Sinica” ECM changes may play a role in hair loss, with differences between males and females.