research High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth
Aminoacridine and Minoxidil together show promise for better hair and nail growth.
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540-570 / 1000+ results research Drug Repurposing Against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study
Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
research Effect of Minoxidil Formulations on Human Scalp Skin Xenotransplants on SCID Mice: A Novel Pre-Clinical In Vivo Assay for Androgenetic Alopecia Research
Minoxidil solution and foam both increase hair growth, but the solution works better than the foam.
research The Risks and Benefits of 5α-Reductase Inhibitors for Prostate Cancer Prevention
5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
research Deoxycholic Acid in Submental Fat Reduction: A Review of Properties, Adverse Effects, and Complications
Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.
research Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression
Lurasidone is effective for bipolar depression and schizophrenia, but more safety data is needed.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Alopecia Areata in Skin of Color Patients: New Considerations Sparked by the Approval of Baricitinib
The paper concludes that the new medication baricitinib needs further testing in a more diverse group of patients with alopecia areata.
research Drug-Induced Hair Loss: Analysis of the Food and Drug Administration’s Adverse Events Reporting System Database
Certain medications, including some immune drugs, contraceptives, and hair loss treatments, are often linked to hair loss.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.
research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Androgens and Acne: Perspectives on Clascoterone, the First Topical Androgen Receptor Antagonist
Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
research 5% Minoxidil: Treatment for Female Pattern Hair Loss
5% minoxidil foam effectively treats female hair loss.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Medications Mostly Associated With Ejaculatory Disorders: Assessment of the EudraVigilance and Food and Drug Administration Pharmacovigilance Databases Entries
Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
research Drug News
Actemra is approved for a specific artery condition, HIV treatment adherence has improved, women may pay more for a hair loss product, and incorrect dosing of blood thinners can be risky.
research Topical Drugs Regrow Hair In Mice
Certain topical drugs can regrow hair in mice.
research Applications of the Excimer Laser
The 308-nm excimer laser is effective for skin conditions but needs more research on long-term effects.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Therapeutic Potential of Bimatoprost for the Treatment of Eyebrow Hypotrichosis
Bimatoprost is safe and effective for improving eyebrow hair.
research Hair Loss And Regeneration Performed On Animal Models
Animal models are crucial for learning about hair loss and finding treatments.
research New-Generation Therapies for the Treatment of Hair Loss in Men
New treatments for male hair loss show promise but need more research for safety and effectiveness.
research Laser-Assisted Hair Transplantation: A Status Report in the 21st Century
Lasers in hair transplantation show promise but are not yet standard, with current methods causing some side effects and needles still being preferred for creating recipient sites.
research Cutaneous Toxicities of New Targeted Cancer Therapies: Must Know for Diagnosis, Management, and Patient-Proxy Empowerment
New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.
research Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review
Low-dose oral minoxidil is effective and well-tolerated for treating hair loss.
research Alopecia Areata: The Clinical Situation
Treating alopecia areata is difficult due to limited approved treatments, but new therapies like JAK inhibitors show promise.
research Patient Profile and Treatment Characteristics of Early Ritlecitinib Initiators in the US
This study examined the early integration of ritlecitinib into real-world practice for treating severe Alopecia Areata (AA) following its FDA approval in June 2023. Analyzing data from 150 patients, the study found that 72% were prescribed ritlecitinib by dermatologists, with a patient demographic of over half being female, 52% adolescents, and 78% commercially insured. Notably, 30% had alopecia totalis/universalis, and various comorbidities were present, including autoimmune, atopic, and mental/emotional disorders. Prior to ritlecitinib, 34% of adolescents and 24% of adults had no AA treatments, while others used systemic immunomodulators or corticosteroids. The findings indicate that ritlecitinib is being prescribed to a diverse patient group, offering new opportunities for AA treatment. The study was funded by Pfizer Inc.
research Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia
New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.