March 2023 in “Advances in Cosmetic Surgery” Exosomes, tiny cell-released particles, may help hair growth, but their exact role is unclear, they're not FDA-approved, and their unregulated use can cause side effects.
26 citations,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
15 citations,
March 1998 in “Journal of Public Policy & Marketing” The paper concludes that drug labels should be clear for all, especially for those with low literacy, and suggests aiming for high comprehension test passing rates with diverse test populations.
The conclusion is that hair supplement ingredients may be unsafe and should be disclosed and proven safe before use.
70 citations,
October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
40 citations,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
June 1990 in “Health Marketing Quarterly” Drug companies were interested in advertising directly to consumers to make back their money, but most didn't think it would help and were concerned about negative effects.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
July 2024 in “Skin Appendage Disorders” Certain medications, including some immune drugs, contraceptives, and hair loss treatments, are often linked to hair loss.
September 2023 in “PubMed” Baricitinib is a relatively safe and effective treatment for severe alopecia areata.
7 citations,
October 2020 in “Dermatology practical & conceptual” Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
36 citations,
September 2018 in “Dermatologic Therapy” Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.
15 citations,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
6 citations,
January 2020 in “Dermatology” Finasteride may increase suicide risk; more research needed.
5 citations,
February 2012 in “Aesthetic Plastic Surgery” A man developed skin cancer on his scalp after multiple artificial hair grafts.
Off-label drug use can be risky but sometimes beneficial when standard treatments fail.
February 2013 in “Journal of The American Academy of Dermatology” Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.
February 2013 in “Journal of The American Academy of Dermatology” Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.
February 2013 in “Journal of The American Academy of Dermatology” A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.
March 2019 in “Reactions Weekly” Finasteride may increase risk of suicidal thoughts and self-harm.
33 citations,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
7 citations,
March 2018 in “Dermatology and therapy” Finasteride is considered the best treatment for hair loss, despite side effects.
6 citations,
May 2011 in “Journal of Pharmacy Technology” Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
116 citations,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
68 citations,
April 2002 in “Journal of Alternative and Complementary Medicine” Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.
65 citations,
April 2002 in “Journal of Alternative and Complementary Medicine” Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.
63 citations,
January 2012 in “The European Journal of Contraception & Reproductive Health Care” Some birth control pills have a higher risk of blood clots than others.
58 citations,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.