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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Bariatric surgery patients need careful before and after surgery care for safety and long-term health.

Skin symptoms can indicate endocrine disorders and have various treatments.

High-fructose diets can cause irreversible kidney damage.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Teak seed extract is safe and reduces pain in mice.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Some medicinal plants can help heal wounds and may lead to new treatments.

Zinc is effective for treating various skin conditions, including warts and acne.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Probiotic bacteria improved skin and hair health in aged mice.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.