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    Glossary Fatty Acids

    long chains of carbon and hydrogen in fats (lipids)

    Fatty acids are essential building blocks of fats (lipids) that play a crucial role in the body. They are long chains of carbon atoms with hydrogen atoms attached, and they can be either saturated or unsaturated. These molecules are vital for energy storage, cell membrane structure, and signaling pathways.

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    1. Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development Proceedings of the National Academy of Sciences of the United States of America · 2003 · 93 citations
    2. Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes 2019 · 70 citations
    3. Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production Journal of Investigative Dermatology · 2019 · 40 citations
    4. Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands 2011 · 40 citations
    5. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    6. A Fatty Acid / Protein Complex in Human Hair Nature · 1961 · 19 citations
    7. Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair Lipids · 2014 · 18 citations
    8. GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia Journal of Saudi Chemical Society · 2021 · 5 citations
    9. Fatty acid composition of selected organs of gerbils maintained on a fat‐deficient or fat‐supplemented diet Lipids · 1977 · 4 citations
    10. Effect of hair oils and fatty acids on the growth of dermatophytes and their in vitro penetration of human scalp hair. PubMed · 1970 · 4 citations
    11. Efficacy of a Nutritional Supplement, Standardized in Fatty Acids and Phytosterols, on Hair Loss and Hair Health in both Women and Men Journal of cosmetology & trichology · 2017 · 3 citations
    12. Perturbations in fatty acid metabolism and collagen production infer pathogenicity of a novel MBTPS2 variant in Osteogenesis imperfecta Frontiers in endocrinology · 2023 · 1 citations
    13. Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19) Current developments in nutrition · 2019 · 1 citations
    14. Para rubber seed oil and its fatty acids alleviate photoaging and maintain cell homeostasis International Journal of Cosmetic Science · 2024 · 1 citations
    15. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    16. Fatty acid oxidation fuels mitochondrial respiration to drive epidermal stem cell fate and differentiation Nature Communications · 2026
    17. Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis Journal of Investigative Dermatology · 2026
    18. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    19. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    20. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    21. Dietary Vitamin D Supplementation Improves Hair Follicle Development and Affects Fatty Acid Metabolism in Rex Rabbits Food Science & Nutrition · 2025
    22. ATOMISTIC CHARACTERIZATION OF HEALTHY AND DAMAGED HAIR SURFACES: A MOLECULAR DYNAMICS STUDY OF FATTY ACIDS ON PROTEIN LAYER ChemBioChem · 2024
    23. Evaluation of Adipocyte Fatty acid Binding Protein (A-FABP) Serum Level in Male Androgenetic Alopecia Patients The Egyptian Journal of Hospital Medicine · 2024
    24. 863 Central centrifugal cicatricial alopecia gene expression analysis revealed cholesterol, fatty acid, and mast cell pathways 2019
    25. 923 Molecular phenotyping of lichen planopilaris revealed dysregulation of cholesterol/fatty acid metabolism, fibrosis and mast cell pathways Journal of Investigative Dermatology · 2019
    26. Immunohistochemical localization of fatty acid transporters and MCT1 in the sebaceous glands of mouse skin Institutional Repositories DataBase (IRDB) · 2016
    27. GC-MS Fatty Acid Profile and In silico Studies of Telfairia occidentalis Hook f. (Fluted Pumpkin) and Sphenostylis stenocarpa (African Yam bean) Seeds Oil on Human 5 Alpha Reductase II 2026
    28. Exploring the effects of wetting and free fatty acid deposition on an atomistic hair fiber surface model incorporating Keratin Associated Protein 5-1 2022
    29. 694 Retinoid induced changes in the fatty acid profile of sebum and its effect on bacterial growth Journal of Investigative Dermatology · 2016
    30. Effects of Omega-3 polyunsaturated fatty acids on skin health, hair quality, and feeding behavior in adult Bichon Frises DOAJ (DOAJ: Directory of Open Access Journals) · 2026