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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

Skin aging reflects overall body aging and can indicate internal health conditions.

Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Treatments for melanin disorders exist, but more effective options needed.

BAF200 is essential for proper heart and coronary artery formation.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

THSG from a Chinese plant helps with aging and related diseases.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Dermal adipose tissue in mice can change and revert to help with skin health.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.