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Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A woman had a unique skin growth with hair follicle, oil glands, fat cells, spindle cells, and nerve fibers.

Deleting MPZL3 increases skin oil production and reduces body fat.

Fat from the body can help improve hair growth and scars when used in skin treatments.

An 11-year-old obese girl was diagnosed with lipedematous scalp, a condition with swollen scalp tissue usually found in adult women.

Dermal adipose tissue in mice can change and revert to help with skin health.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Increasing sebum production might help reduce fat and improve metabolism.

Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.

Three white adults had a rare scalp condition with increased fat and sometimes hair loss, suggesting it's not limited to black women and might be more widespread.

Fat cells in the skin help start healing and form important repair cells after injury.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Adipose-derived stem cells can help repair and improve eye tissues and appearance.

Facial rejuvenation surgery has evolved to yield natural results with low complication rates, and more men and older patients are choosing this surgery.

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Adding L-glutamine to the diet of Hanwoo steers may boost their immune system and help them cope with heat.

Children with metabolic syndrome often have skin problems like dark patches, skin tags, stretch marks, infections, acne, and psoriasis, which are linked to obesity and insulin resistance.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

A special hydrogel helps heal skin without scars and regrows hair.