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This article reviews regenerative therapy for treating various types of hair loss and does not present new clinical findings.

Blocking DPP4 can help prevent fat loss and skin fibrosis.

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.

In this case study, a female patient with folliculitis decalvans experienced hair re-growth and relief from symptoms like pain and burning after undergoing autologous fat transplantation, suggesting beneficial effects from stem cell therapy assisted by the inflammatory action of transplanted fat.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.

This study found that mesenchymal stem cells derived from dental pulp and adipose tissue have distinct gene expression signatures that suggest potential target diseases for clinical applications.

This study examined aging hair follicle stem cells in mice and found that inflammation reduction in dermal white adipose tissue can stimulate regenerative behavior, highlighting its role in hair follicle aging.

This study reported that autologous whole fat injection in the scalp considerably increased hair growth in patients with androgenetic alopecia.

This study highlights the potential of fat injections for treating alopecia, as they may promote hair regrowth, reduce inflammation, and exhibit limited adverse effects, suggesting efficacy and safety in managing the condition.

This review discusses the effectiveness of adipose-derived stem cells in treating alopecia, reporting on various clinical studies but presenting no new clinical results.

This review highlights the wide-ranging clinical uses of autologous fat transplantation in regenerative medicine, noting its advantages such as easy harvesting, tissue integration, and stem cell abundance, and discusses its future in personalized therapeutic regimens for tissue repair.

In this study of patients with Androgenic Alopecia, micro-grafts containing HD-AFSCs resulted in significantly improved hair density and follicle count over 11 months compared to a saline solution, suggesting a potential alternative therapy for hair regrowth.

This study found that TGFbeta is a key pathway causing age-related loss of dermal fat's antimicrobial function, suggesting that targeting TGFBR might help restore skin defense against infections in older age.

This review discusses the potential effectiveness of cell therapy for hair loss, highlighting promising early findings but emphasizing that more research is needed to explore specific therapies like autologous fat grafting and mesenchymal stem cells.

This review discusses the connection between hair follicles and dermal adipose tissue, suggesting that improving the adipogenic environment could be important for treating alopecia and enhancing hair restoration procedures, but reports no new results.

This study found that mature dermal adipocytes have high plasticity, undergoing dedifferentiation and redifferentiation, which plays a significant role in hair cycling and wound healing.

This review discusses the roles and mechanisms of tissue-resident regulatory T cells in immune regulation and tissue homeostasis, but reports no new experimental results.

This study found that their novel 3D-imaging method, ASAXA-μCT, identified shrinkage of sweat glands as a key factor in skin aging, which leads to dermal defects, decreased elasticity, and increased wrinkling and sagging.

This study found that MPZL3 knockout mice showed reduced dermal white adipose tissue and increased sebocyte proliferation, suggesting a regulatory role for MPZL3 in lipid metabolism balance between adipocytes and sebocytes.

Researchers created a new mouse model for studying scleroderma.

This article discusses the effectiveness of fat transfer for facial rejuvenation across all ethnicities, emphasizing its potential as both a primary method and a complement to traditional techniques, but reports no new clinical findings.

This study investigates the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel mouse model but reports no new results, highlighting the need for further research on its function during the hair cycle.

This study discovered that adipose tissue infiltration at the isthmus level appears significantly more often in frontal fibrosing alopecia cases compared to controls, suggesting a potential role in the condition's pathology.

This study found that adult mouse dermis can be reprogrammed by epidermal cues to resemble neonatal dermis, with changes in fibroblast proliferation and extracellular matrix composition.

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

This article reviews the potential of adipose-derived and Wharton’s jelly stem cells in alopecia treatment but presents no new clinical findings, highlighting their potential benefits and limitations in regenerative medicine.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

In this case report, researchers observed that scalp injection of adipose tissue may have a positive effect on hair regrowth in a patient with trauma-induced alopecia.