January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
252 citations,
April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
72 citations,
December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
56 citations,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
24 citations,
February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
23 citations,
November 2007 in “Journal of cosmetic dermatology” Both mesotherapy treatments reduced under-chin fat equally and were safe with mild side effects.
17 citations,
September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
16 citations,
December 2019 in “Journal of Cellular and Molecular Medicine” Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
16 citations,
January 2016 in “International Journal of Medical Sciences” Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
15 citations,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
4 citations,
May 2012 in “Tissue Engineering and Regenerative Medicine” Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
8 citations,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
April 2018 in “Journal of Investigative Dermatology” Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
19 citations,
April 2015 in “International Journal of Molecular Sciences” The research identified genes and pathways important for sheep wool growth and shedding.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
January 2023 in “Journal of orthopedics & bone disorders” Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
25 citations,
May 2020 in “Stem Cells Translational Medicine” ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
April 2019 in “Journal of Investigative Dermatology” Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
April 2018 in “Journal of Investigative Dermatology” Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.