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CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Insulin resistance linked to obesity may increase COVID-19 severity.

Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Quercetin may help with PCOS symptoms, but more research is needed.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Better hair care products are needed to protect against grooming and chemical damage.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Herbal nano-formulations show potential for effective skin delivery but need more research.

The document suggests that the traditional understanding of hair growth cycles and alopecia may be inaccurate and that blood supply plays a significant role in hair growth and loss.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.