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Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Medications for PCOS don't seem to raise heart disease risk.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

A new gene mutation causes insulin resistance in a girl and her mother.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.