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The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

High levels of androgens during early development may cause PCOS-like symptoms.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Quercetin may help with PCOS symptoms, but more research is needed.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Testosterone improves mood and thinking skills; finasteride has no effect.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.

The document concludes that more research is needed to fully understand the causes of PCOS.