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Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Quercetin may help with PCOS symptoms, but more research is needed.

Some alternative treatments for hair loss might work, but more research is needed.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Minoxidil may cause heart issues in animals and humans.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.