9 citations
,
June 2020 in “Cell stem cell” Skinny fat cells help wounds heal faster by releasing fatty acids.
November 2023 in “Journal of cosmetic dermatology” Fat transplants using a patient's own fat can rejuvenate and repair tissues effectively.
408 citations
,
February 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
11 citations
,
May 2015 in “Stem Cells Translational Medicine” Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
14 citations
,
October 2012 in “Clinics in Plastic Surgery” Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.
June 2021 in “Research Square (Research Square)” Using fat-derived cells to treat hair loss increased hair density and thickness without side effects.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
45 citations
,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
45 citations
,
May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
30 citations
,
September 2017 in “Current stem cell research & therapy” Adipose-derived stem cells (fat cells) show promise in treating hair loss in both men and women.
13 citations
,
February 2017 in “Science” Turning scar-forming cells into fat cells can reduce scarring.
May 2016 in “Journal of Investigative Dermatology” Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
22 citations
,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
3 citations
,
September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
March 2022 in “Indian Journal of Animal Research” Dog hair follicle stem cells can turn into fat cells.
6 citations
,
August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
May 2017 in “Journal of Investigative Dermatology” Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
May 2018 in “Journal of Investigative Dermatology” Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
18 citations
,
January 2000 in “Food Science and Technology Research” Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.
9 citations
,
April 2019 in “International Journal of Molecular Sciences” Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.
238 citations
,
April 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
124 citations
,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
42 citations
,
October 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
2 citations
,
April 2017 in “PubMed” Fat cells near hair follicles may affect hair growth and could help treat baldness.
218 citations
,
September 2014 in “Experimental Dermatology” Skin fat cells help with skin balance, hair growth, and healing wounds.
22 citations
,
April 2017 in “Cell Stem Cell” Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
30 citations
,
February 2019 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.