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Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Mild thyroid issues don't affect the metabolism and hormones of women with PCOS.

Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.

Darkened knuckles can be an early sign of insulin resistance.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Melatonin may help treat PCOS symptoms in rats.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.