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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Minoxidil effectively lowers blood pressure with few side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

The document suggests changing medical education to balance generalists and specialists, focusing on patient needs.

Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.

Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

Adult acne severity is influenced by stress, skin sensitivity, makeup, stopping oral contraceptives, and requires female-specific treatment guidelines.

Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.

The article explains how to rebuild parts of the head and face and how to transplant hair to cover scars, highlighting the need for careful planning and choosing the right method for each patient.

Baldness might be caused by scalp weight pressing on hair follicles.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Secukinumab for psoriasis unexpectedly caused increased hair growth in a patient.