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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.

Transplant patients often get skin problems, with treatments varying by condition.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

The document concludes that proper diagnosis and treatment of nonscarring alopecias can improve quality of life and hair regrowth is possible as the hair follicle remains intact.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Multi-pass laser skin treatments improved healing, reduced pain, and had no major complications.

The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.

Aloe vera gel effectively treated mange in camels.

Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.

Scalp reduction surgery is safe and effective for certain patients with hair loss, leading to dense hair coverage and high satisfaction.

Hair and nails are skin parts that develop early and serve protective and functional roles.

The U.S. soybean industry wanted government help due to foreign competition, while the jojoba industry was growing and expected to stabilize.

High doses of certain vitamins can cause serious side effects and health risks.

SMP creates illusion of full hair, addressing various issues and bringing happiness to those with thinning hair.

Finasteride and low-level laser therapy are similarly effective for frontal pattern hair loss.

Manage hair loss from trauma with scalp expansion, advancement flaps, and hair transplantation.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.