122 citations,
April 2020 in “American Journal Of Pathology” The document reviewed the pathobiology of skin aging, identifying it as a degenerative process influenced by intrinsic and environmental factors, leading to structural changes such as epidermal thinning, loss of dermal papillae, and decreased collagen and elastin, which contribute to wrinkles and sagging. It highlighted the role of stem cell dysfunction, genetic factors, and immune system decline in skin deterioration, noting increased susceptibility to infections and skin cancer. The review argued for recognizing skin aging as a disease due to its health implications and variability among individuals. It also discussed the psychological impact of skin aging and advocated for public health strategies to mitigate its progression. The document emphasized the complex interplay between skin aging, stem cell function, and immune response, suggesting potential interventions like targeting sirtuins to reverse aging effects.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
79 citations,
December 2017 in “Cosmetics” Effective sunscreen formulations can reduce skin absorption and enhance protection.
34 citations,
September 2020 in “Clinical, cosmetic and investigational dermatology” Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
6 citations,
May 2020 in “Nutrients” Eating fewer calories may slow skin aging and improve skin health through various biological changes.
6 citations,
January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
4 citations,
April 2020 in “Reports of Practical Oncology & Radiotherapy” Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.
4 citations,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
3 citations,
April 2020 in “Clinical endocrinology and metabolism journal” Imaging helps detect adrenal gland issues and monitor treatment in congenital adrenal hyperplasia, and can identify tumors affecting fertility.
1 citations,
April 2023 in “Scientific Reports” Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
February 2024 in “World journal of stem cells” Adipose-derived stem cells can help repair and improve eye tissues and appearance.
October 2023 in “Cancers” Skin cancer in sun-exposed areas is more likely to come back.
August 2023 in “Diagnostics” Ultra-high-frequency ultrasound effectively evaluates the impact of hyaluronic acid fillers in reducing nasolabial fold wrinkles over time.
January 2022 in “Sustainable development goals series” The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
159 citations,
September 2001 in “European Journal of Cancer Care” Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.
4 citations,
January 2008 in “Facial Plastic Surgery” Improve skin paddle appearance after head and neck reconstruction using tissue expansion, rearrangement, and flaps.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
81 citations,
August 2011 in “Journal of The American Academy of Dermatology” Latanoprost 0.1% may effectively treat hair loss.
5 citations,
May 2004 in “International Journal of Cosmetic Science” Versican is important for hair growth and could help find new hair regrowth treatments.
A hair transplant using hair from the back of the head and pubic area was successful in creating a feminine hairline for a male-to-female transgender person.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
94 citations,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
45 citations,
September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
15 citations,
March 2012 in “International journal of nanomedicine” Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
3 citations,
July 1997 in “Current problems in dermatology” Hair restoration surgery has evolved over time, with a focus on natural-looking results and managing patient expectations, while also considering potential complications and the lifelong progression of male pattern baldness.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.