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This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.

This chapter discusses the composition, biocompatibility, and production methods of biomaterials like collagen, chitin, and silk for dermal substitutes, focusing on preclinical and clinical research, but reports no new clinical results.

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.

This review article summarizes recent strategies to enhance the precise control of CRISPR/Cas9 gene editing, addressing tissue-specific challenges and off-target effects by exploring various activation methods like cell-specific promoters and small molecules.

This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.

In this study, researchers reviewed recent advances in using nanoencapsulation technology to improve the pharmacological treatment of alopecia, suggesting its potential to enhance drug delivery and reduce adverse effects compared to conventional methods.

This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.

The authors suggest that nanoparticles, synthesized from biological sources, may enable targeted cancer therapy with fewer side effects than traditional methods.

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.

This review highlights the potential of nanoemulgel as a promising drug delivery system for lipophilic drugs, but presents no new experimental results; it discusses composition, preparation methods, and applications.

In this study, researchers explored the use of natural materials in scaffold construction for dental bone preservation, suggesting it could offer better biocompatibility and bone regeneration compared to traditional grafting methods.

This review highlighted the potential of silver nanoparticles' antibacterial properties across biomedical, pharmaceutical, and dental applications, and emphasized plant-based biosynthesis methods as eco-friendly alternatives to conventional nanoparticle production despite existing toxicity concerns.

This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.

This review highlights the potential of inorganic nanoparticle-based scaffolds as innovative tools for advanced wound care, emphasizing their ability to provide antimicrobial action and regenerative support, while also discussing fabrication strategies and challenges in optimizing their clinical application.

This review summarizes research on the use of Platelet-Rich Plasma for treating discogenic low back pain, showing potential therapeutic benefits but indicating varied results across studies and a need for more objective evaluation methods.

This review presents recent advancements in bio-degradable polymers made through green chemistry, highlighting eco-friendly raw materials and methods, while also identifying challenges and future research areas to enhance their sustainability and commercial viability.

In this study, hair follicle germs containing vascular endothelial cells showed improved hair regeneration and morphogenesis-related gene expression in mice, suggesting a promising strategy for hair regenerative medicine.

Light can be used to stimulate ear hair cells, improving speed and consistency over previous methods.

This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.

New microneedle method improves hair regrowth treatment delivery.

This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.

This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.

This study presents a modified method for synthesizing ~1 nm zinc oxide nanoparticles within the pores of SBA-11, maintaining the mesoporous structure without requiring alcohol reflux or basic solution reaction steps.

This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.

This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.

This chapter reviews bioengineered human hair follicles and discusses the pros and cons of different 3-D bioprinting methods, but reports no new experimental findings.

This review discusses the properties and bioextraction methods of chitin and chitosans, emphasizing their potential use in eco-friendly cosmetic manufacturing and reports no new experimental findings.