research Impact of Type 2 Cytokines on the Keratinocytes-Staphylococcus Aureus Interaction
Type 2 cytokines IL-4 and IL-13 increase skin's vulnerability to Staphylococcus aureus, which could be important for treating atopic dermatitis.
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research IL-9/IL-9R Signaling as a Novel Regulator of Human Hair Follicle Growth and Immune Privilege
IL-9/IL-9R signaling can negatively affect human hair growth and may be a target for treating hair loss conditions.
research Interest of a Cinchona Succirubra Extract and Its Association with Caffeine in Hair Loss
Cinchona succirubra extract with caffeine improves hair growth and reduces hair loss.
research Clinical and Immunological Impact of Booster Immunization With Recombinant mRNA Vaccines for SARS-CoV-2 in Patients With Pemphigus and Bullous Pemphigoid
Booster shots of mRNA vaccines for COVID-19 increased protective antibodies without worsening autoimmune skin conditions in patients.
research Response to Ritlecitinib Treatment Based on Salt Improvement Scores in Patients With Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib significantly improves scalp hair regrowth in alopecia areata patients over time.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.
research Clinical Technique and Outcomes of Platelet-Rich Plasma Application for Treatment of Androgenic and Scarring Alopecia, Acne Scarring, Melasma, and Facial Rejuvenation: A Prospective Multicenter Study
Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
research Prostacyclin Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Treprostinil, a drug, can delay wound healing in healthy cells but doesn't affect diabetic foot ulcer cells, suggesting further research could help understand its role in treating these ulcers.
research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research An Innovative Phase 1b Trial Demonstrating Proof-of-Pharmacology for Two Novel IRAK4-Inhibitors Using a Local and Systemic Driven Immune Response
Two new IRAK4-inhibitors effectively reduced skin inflammation and immune response markers in healthy volunteers.
research Impact of Urban Pollution and Chronic Sun-Exposure on Skin Ageing in Chinese Women
Urban pollution and sun exposure speed up skin aging and wrinkle formation in Chinese women, with pollution's effects becoming significant after age 45.
research Prospective Study of the Metabolic Effects of Tumescent Liposuction
Tumescent liposuction reduces waist and hip size but doesn't significantly change metabolic markers, though it may slightly improve blood pressure and certain protein levels.
research Low Temperature and MTOR Inhibition Favor Human Epidermal Stem Cell Maintenance
Keeping human skin stem cells is easier with low temperatures and mTOR inhibition.
research Cryo-EM and Molecular Dynamics of TRPV3 Channel in Activated State Reveal Structural Features Implicated in Severe Itch and Hyperkeratosis
The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
research Baricitinib For Alopecia Areata
Baricitinib is effective in promoting hair growth in severe alopecia areata.
research Recent Advances in the Genetics of Alopecia Areata
New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.
research Empathic Disequilibrium Is Related to Lower Levels of Oxytocin in Hair
People with an imbalance between their cognitive and emotional empathy have lower levels of the hormone oxytocin in their hair.
research Autophagy Controls Epidermal Tumour Formation and Hair Follicle Stem Cell Activation
Autophagy in skin cells is important for preventing inflammation, skin tumors, and controlling hair growth timing.
research Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research Activation of Olfactory Receptor 2A4/7 by Cyclohexyl Salicylate Promotes Human Hair Follicle Growth
The fragrance cyclohexyl salicylate helps promote hair growth and increase hair stem cell numbers.
research Sephardic Ancestry in Recessive Dystrophic Epidermolysis Bullosa Individuals Carrying the Prevalent c.6527insC Mutation
Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.
research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes
Dynlt3 is important for melanosome transport and skin coloration.
research Effects of a LED Light Therapy Mask on an Ex Vivo Skin Model and Clinical Signs of Aging
The LED light therapy mask improved skin elasticity and reduced signs of aging in a test and in women aged 40-60.
research Three-Dimensional Culture of Dermal Papilla Cells Improves Their In Vitro Angiogenic Activity
Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
research Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Affect Stem Cells in Human Scalp Hair Follicles
Fish-derived collagen may help hair grow longer and affect hair stem cells, while bovine collagen could benefit hair stem cell maintenance, potentially aiding in hair loss conditions.
research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research Nutrient and Stress Sensing as Novel Physiological Regulator of Human Hair Pigmentation and Greying: Role of mTORC1 Activity
Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.
research The Spectrum of PLEC Sequence Variants and Related Plectinopathies Including Novel Association with Epidermolysis Bullosa Pruriginosa
Neutrophils quickly respond to skin injury.
research Regulation of the Lipidome and Lipid Metabolism in Prematurely Senescent Human Dermal Fibroblasts
Aging skin cells change their lipid profiles due to stress, affecting skin health.
research Alopecia X in Dogs: Report of Seven Cases
The conclusion is that different treatments improved hair growth in dogs with Alopecia X, but results varied and not all dogs had complete hair regrowth.