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A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.

The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.

Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Botulinum toxin injections can help treat common hair loss in men, but more research is needed to confirm this and understand how it works.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Advanced techniques and technologies can improve burn wound healing, but more research is needed.

Teak is a durable, termite-resistant wood with medicinal benefits.

The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.

Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Blocking a specific protein signal can make hair grow on mouse nipples.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.