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Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Severe alopecia areata greatly impacts quality of life, mental health, and daily activities.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Targeted cancer therapies often cause serious skin problems that need careful management.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Current treatments for alopecia show no significant long-term benefits.

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Use finasteride, dutasteride, and minoxidil for hair loss treatment.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.

Minoxidil effectively and safely treats patchy hair loss, but more research needed.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Hair restoration techniques like follicular unit transplant surgery and follicular unit extraction are effective, with ideal graft placement density between 20-30 units per cm². Medications like Minoxidil and Finasteride can help maintain and regrow hair.

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

Researchers created a new tool to measure the effects of alopecia areata from the patient's view, focusing on hair loss, daily life, and emotional health.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Patients felt happier with their looks and younger after hair transplant surgery, but their well-being and social life didn't change much.

Isotretinoin was not effective in treating facial lichen planopilaris.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

Alopecia areata severely impacts quality of life, causing anxiety, depression, and work impairment.

Use trichoscopy to diagnose hair loss; treat with minoxidil, finasteride, or dutasteride; consider platelet-rich plasma and spironolactone.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Continuous baricitinib is needed to keep hair regrowth in severe alopecia areata.