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In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.

In this study, a shampoo and hair tonic containing the botanical extract blend Asacurin100 reduced hair loss and improved scalp health in 35 male participants with androgenetic alopecia, without serious side effects, suggesting potential efficacy that warrants larger trials for confirmation.

In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.

In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.

This study developed a herbal shampoo using Reetha, Amla, Neem, Bringraj, Jatamanasi, and Aloe vera, reporting that the shampoo met pharmacognostical standards and showed increased hair growth activity, excellent washing and conditioning effects at 1% concentration, and stability with no skin irritation.

This study analyzed the phytochemical content of two Portulaca species and found that extracts from Portulaca oleracea L. and Portulaca grandiflora H. demonstrated suitable characteristics for hair tonic formulations, meeting Indonesian National Standards for cosmetic products.

In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.

This study evaluated cucumber extract shampoos and found they meet physical quality standards and exhibit strong antifungal activity against Candida albicans fungi, with efficacy increasing with higher concentrations of cucumber extract.

This study evaluated a hibiscus-based herbal shampoo formulation and found it to have effective cleansing and conditioning properties, mild antimicrobial benefits, and good physical stability, positioning it as a natural alternative to synthetic shampoos.

This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.

This study focused on the formulation of topical gels containing Equisetum arvense extract, evaluating their consistency and preparation using gelling agents for potential application in enhancing drug delivery to wound sites.

In this study, researchers reported significant hair growth in an 8-year-old with hypotrichosis simplex of the scalp after treatment with a combination of oral botanical extracts and minoxidil, marking the first documented use of botanical extracts as a potential therapeutic approach for this condition.

The study found that a novel mixture of mastic gum and peppermint extract increased hair growth and gloss in C57BL/6 mice, showing potential as a botanical alternative for promoting hair health.

This study found that hydroalcoholic extracts of Bacopa monnieri demonstrated significant antimitotic activity in an Allium cepa model, suggesting potential comparable effects to the standard drug methotrexate.

In this study, researchers developed a shampoo using ambon banana peel and green tea leaves, reporting that it showed positive characteristics and was safe for addressing hair loss, with optimal viscosity levels achieved in certain formulations.

In this study, researchers developed and evaluated a topical dutasteride gel for treating male pattern baldness, finding that a formulation with 10% garlic extract showed the most promising results in promoting faster hair growth compared to other formulations tested.

This study demonstrated that several botanical extracts possess antioxidant properties, reducing oxidative stress and lipid oxidation in scalp treatments, with rosemary extract showing potential to improve scalp condition in a 4-week consumer trial.

This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.

This study evaluated herbal hair gels made with extracts of flax seed and curry leaves, finding that the formulations offered good texture, stability, and sensory appeal while promoting healthy hair and scalp without irritation, making them suitable for regular use.

This study found that the F6 formulation of a hair tonic containing EDS and ATG extracts produced the most significant hair growth in rabbits, without causing skin irritation and remaining stable throughout the observation period.

In this study on Wistar rats, ginger and celery extracts at the tested dosage did not significantly affect hair growth onset, duration, or regrowth, nor did they cause significant inflammation, despite the presence of bioactive phytochemicals in the extracts.

The research reported that applying treatments with wild peach leaf extract during hair dyeing improved hair's tensile strength, thickness, gloss, and protective qualities in a concentration-dependent manner, suggesting potential for use in natural hair cosmetics.

This review explored the causes of hair graying and evaluated how plant-derived extracts and phytochemicals might alleviate it, noting that certain compounds showed potential in enhancing melanocyte function, reducing oxidative stress, and influencing stress-related pathways based on experimental evidence.

This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.

In this case report, a 6-year-old boy with hidrotic ectodermal dysplasia 2 caused by GJB6 mutations showed no significant hair improvement with age, despite treatment with botanical extracts and Minoxidil.

This study explored the effects of hair tonics made from a combination of kelor leaf and fragrant pandan leaf ethanol extracts on rat hair growth, finding that these combinations influenced hair growth when compared to single extract formulations over 28 days.

This study highlights the growing issue of hair loss around the world and explores the potential of using certain herbs, such as Ficus religiosa and coriander seeds, as natural treatments to promote hair growth and manage hair loss, particularly in India, with minimal side effects.

In this study, researchers reported that an herbal extract with dihydroquercetin glucoside, epigallocatechin gallate glucoside, zinc, and glycine showed similar effectiveness and safety to minoxidil in treating androgenetic alopecia over 24 weeks, with no significant differences in hair growth outcomes between the groups.

The study developed a hair cream using extracts from plants like Hibiscus rosa sinensis and Nigella sativa, reporting that it may protect the scalp and hair by providing antimicrobial effects, promoting hair growth, and preventing hair fall and graying.

This narrative review reports that well-selected plant extracts and their active compounds may improve hair health by promoting hair growth and preventing hair loss, potentially aiding in developing targeted therapies for alopecia.