In this study, perilla seed extract obtained through supercritical fluid extraction was found to promote hair follicle cell proliferation and downregulate key genes linked to androgenetic alopecia, showing potential as a natural treatment for hair loss in vitro.
July 2025 in “Chinese Journal of Dermatology” This study concluded that the effectiveness and safety of a domestic follicular extraction system were similar to conventional follicular unit excision in patients undergoing hair transplant surgery for androgenetic alopecia.
June 2025 in “Jundishapur Journal of Natural Pharmaceutical Products” This study optimized the extraction process and established quality standards for Pomelo peel essential oil from Vinh Long, Vietnam, identifying specific conditions that improved extraction yield and validating a high-precision method for limonene quantification.
April 2025 in “The Journal of Agriculture and Development” In this study, researchers optimized the extraction conditions for polyphenols from the medicinal herb Eclipta prostrata, achieving the highest polyphenol content under specific conditions of temperature, solvent concentration, and time, and found the extract to have significant antioxidant activity.
This study explored Black Sea shark liver oil-based emulgels, finding that the addition of borage oil (Gel 2) enhanced the anti-inflammatory and wound healing properties compared to shark liver oil alone (Gel 1) and a reference diclofenac gel, suggesting promising eco-friendly applications in dermatocosmetics.
January 2025 in “International Journal of Molecular Biology and Biochemistry” In this study, researchers found that the Shindai method effectively extracts keratin from human hair, with female hair yielding more keratin than male hair. The extracted keratin showed high absorption with UV spectrometry and was confirmed as α-keratin through SDS-PAGE analysis.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This study developed plant-pigment-based shampoos using extracts from Neem, Fenugreek, Hibiscus, and Butterfly Pea, which demonstrated stability, antimicrobial properties, and potential scalp benefits such as hair growth promotion and dandruff reduction, making them a promising alternative to synthetic dyes.
November 2024 in “BMC Surgery” This article notes the increasing incidence of androgenetic alopecia in males and the growing acceptance of follicular unit extraction as a treatment, but reports no new clinical results.
November 2024 in “Stem Cell Research & Therapy” A new method improves the isolation of hair follicle cells for better hair growth research.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.
September 2024 in “Zagazig University Medical Journal” This study concluded that incorporating platelet-rich plasma into follicular unit extraction improved scar tissue texture and quality but did not significantly enhance hair restoration results in non-androgenic alopecia.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” This case report detailed a successful treatment involving contracture release and expanded neck flap reconstruction for a patient with severe neck contracture and beard alopecia from past thermal burns, highlighting improved skin quality and hair regrowth following follicular unit extraction.
July 2024 in “Deleted Journal” This study found that using PRP with the FUE method of hair restoration led to better graft survival, aesthetic outcomes, and patient satisfaction compared to not using PRP.
May 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that combining hair transplantation with PRP therapy resulted in better quality and increased growth of new hair, while also speeding up skin healing and reducing hair loss post-transplant.
March 2024 in “Revista Argentina de de Cirugía Plástica Estética y Reparadora” In this study, researchers describe the FUE method of hair micrografting, which involves extracting and implanting follicular units using advanced tools, leading to more natural results, quicker recovery, and less damage to donor sites.
January 2024 in “Authorea (Authorea)” In this retrospective study of 1,415 male hair transplant patients, punch technology improvements for the FUE method were associated with an increased number of total grafts and multi-hair follicular units over time, making FUE a preferred choice for hair transplantation.
This review discusses current therapies for androgenetic alopecia, focusing on hair transplantation methods like FUT and FUE, but does not present new clinical results.
January 2024 in “International Journal of Trichology” This study found that regardless of alopecia type, follicular unit extraction resulted in good patient satisfaction concerning appearance and visual age.
December 2023 in “International Journal of Science and Research (IJSR)” In this observational study, researchers at a dental and craniofacial hospital found that the FUE technique for beard and moustache transplants is effective and safe, with minimal complications such as pinpoint white scars in some patients but no significant issues like infection or numbness.
November 2023 in “Facial Plastic Surgery” This study discusses the advantages and disadvantages of two hair graft harvesting methods, strip follicular unit transplantation and follicular unit excision, highlighting their implications for creating effective surgical plans for hair restoration without providing specific new results.
In this study, the SFE-4 extract from coffee pulp demonstrated potential effects for treating androgenetic alopecia by enhancing cell proliferation and gene expression related to hair growth pathways in vitro, using human hair follicle dermal papilla and prostate cancer cells.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
June 2023 in “Journal of Cosmetic Dermatology” This study found that FUE megasession with a specific surgical design is an effective and satisfactory treatment for Asian patients with high-grade male androgenetic alopecia, achieving natural hair density and high patient and doctor satisfaction, with minimal side effects.
April 2023 in “Research Square (Research Square)” This study found that FUE hair transplantation for male androgenetic alopecia results in a high hair follicle survival rate and patient satisfaction, with a low complication rate.
January 2023 in “Skin appendage disorders” The case study reports a patient with acute telogen effluvium in the donor region post-hair transplant, highlighting trichoscopic findings that aid in diagnosis and reassuring the self-resolutive nature of this condition.
This study found that follicular unit extraction can be safely performed without bupivacaine and nerve blocks, using lignocaine with adrenaline as an effective anesthetic for patients with certain grades of androgenetic alopecia.
January 2023 in “Journal of Cutaneous and Aesthetic Surgery” In this case report, follicular unit extraction successfully treated stable segmental vitiligo in the inguinoscrotal region.
July 2022 in “Journal of Cosmetic Dermatology” This study found that follicular unit extraction, with or without platelet rich plasma, is effective for hair restoration in cicatricial alopecia, though PRP does not significantly impact graft survival rates.
June 2022 in “Ain Shams medical journal” This study found that incorporating platelet-rich plasma in hair transplant procedures for cicatricial alopecia improved patient satisfaction and hair growth outcomes compared to procedures without it.
This case report and literature review concluded that using the follicular unit extraction technique for hair transplants in androgenetic alopecia patients yields satisfactory aesthetic results and high patient satisfaction over 12 months.