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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

The Rotterdam Study aims to understand various diseases in older adults.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

PGD2 stops hair growth and is higher in bald men with AGA.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Fungi-produced compounds can change plant root growth.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Researchers created human hair follicles using a new method that could help treat hair loss.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.