February 2025 in “Journal of Fundamental and Applied Pharmaceutical Science” In this experimental study, the researchers developed and evaluated a hair tonic made from mangosteen peel extract, finding that all four tested formulations showed suitable physical characteristics and met standard requirements for attributes like pH, viscosity, and stability.
January 2025 in “International Journal of Molecular Sciences” In this study, researchers found that fenugreek seed extract reduced prostate size, DHT levels, and cell proliferation in a testosterone-induced BPH rat model while modulating various genetic expressions, suggesting its potential as an alternative treatment for benign prostatic hyperplasia.
December 2024 in “Animals” In this study, Tithonia diversifolia extract was found to improve certain digestive parameters in crossbred sheep but did not enhance growth performance, as the improvements in digestion did not translate into increased body weight or feed conversion.
November 2024 in “Journal of Investigative Dermatology” Reishi mushroom extract may help treat hair loss.
November 2024 in “Applied Sciences” This study suggests that a supercritical CO2 extract from wild-strawberry-processing waste may be an innovative and sustainable ingredient for cosmetic applications, particularly in treating androgenic-related skin conditions.
October 2024 in “International Journal of Molecular Sciences” In this study, Rosa rugosa water extract improved hair length and thickness in a mouse model of DHT-induced alopecia by enhancing the expression of hair growth-promoting factors while inhibiting growth-suppressive proteins, suggesting its potential as a natural therapy for hair loss prevention.
October 2024 in “Current Issues in Molecular Biology” In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.
July 2024 in “International Journal of Advanced Research in Science Communication and Technology” This study explored the antibacterial and wound-healing effects of an 80% methanol extract from Hibiscus micranthus leaves, finding it effective against several bacterial strains and beneficial for wound healing in rats.
May 2024 in “Journal of functional foods” In this laboratory study, coffee bean residue extract was observed to promote the proliferation of human hair follicle dermal papilla cells by activating autophagy, showing potential for treating hair growth disorders and hair loss.
April 2024 in “The journal of phytopharmacology” This study found that extracts from orchid calluses can stimulate hair follicle growth and enhance the proliferation of hair follicle stem cells in vitro, suggesting potential applications in sustainable hair care products using natural bioactive compounds.
March 2024 in “Journal of biobased materials and bioenergy” In this study, tea tree oil was found to have substantial antibacterial activity and promote proliferation and migration of hair follicle stem cells in vitro, indicating potential benefits for treating scalp alopecia areata.
March 2024 in “Journal of Evidence-Based Integrative Medicine” This study found that a hair tonic containing 1% teak leaf extract significantly increased hair growth and user satisfaction in men with androgenic alopecia after 24 weeks, without causing adverse effects, and was comparable to the standard treatment, minoxidil.
December 2023 in “JSFK (Jurnal Sains Farmasi Klinis)/JSFK (Jurnal Sains Farmasi dan Klinis)” This study found that a hair tonic formulated with 0.3% cocoa bean extract demonstrated the best physical stability and effectively promoted hair growth in mice, with results comparable to a positive control when used twice daily for two weeks.
September 2023 in “International journal of molecular sciences” In this study involving ICR mice, researchers found that Korean red pine bark extract improved cognitive functions impaired by TMT through mechanisms like antioxidant system protection, cholinergic and synaptic support, mitochondrial regulation, and reduction of neuro-inflammation and apoptosis.
July 2023 in “Research journal of pharmacy and technology” In this study on male rabbits, a hair tonic formulated with delipidated ethanol extract of Capsicum frutescens L. leaves at concentrations of 5%, 10%, and 20% promoted hair growth more effectively than a placebo and similar to 2% Minoxidil at the highest concentration.
June 2023 in “Antioxidants” This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
January 2023 in “Faculty of 1000 Research Ltd” Aloe vera extract helps heal burn wounds faster in rats.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.
This study found that an herbal extract from Marking nuts, when compared to a standard drug, effectively inhibited the dandruff-causing organism Malassezia furfur and promoted hair growth on mice, suggesting potential use for dandruff treatment and hair rejuvenation.
January 2022 in “Faculty of 1000 Research Ltd” Aloe vera may help heal burns by boosting skin cell growth.
December 2020 in “Daehanhanuihakoeji” This study found that Rumex japonicas Houttuyn ethanol extract may promote hair growth and protect against oxidative stress-induced hair damage in mice and HaCaT cells.
January 2020 in “Cosmetics” This study found that Ecklonia cava extract increased skin hydration and decreased redness, suggesting potential benefits for protecting and repairing scalp skin from pollutant-induced damage.
January 2019 in “Journal of Pharmacognosy and Phytochemistry” This study identified 14 different phytoconstituents in the methanolic fruit extract of Citrullus colocynthis, suggesting its potential pharmacological importance.
October 2018 in “IOP conference series. Materials science and engineering” In this study, treatment 3 using coffee extract resulted in faster hair growth and greater hair weight in test animals over 21 days compared to other treatments.
This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.
North American ginseng extract helped regrow hair in balding mice.
January 2008 in “Lishizhen Medicine and Materia Medica Research” This study found that the n-butanol extract from Untica mairei Levl's roots significantly inhibited 5α-reductase activity in an in vitro model using rat prostate enzyme.
January 2007 in “Sen'i Gakkaishi” This study found that Mf-rich-fiber in human hair underwent significantly greater degradation by proteases than Ma-rich-fiber, especially when treated with Proteinase K.
49 citations
,
November 2014 in “Journal of Medicinal Food” In this study, red ginseng extract and its ginsenosides enhanced human hair follicle cell proliferation and countered dihydrotestosterone-induced suppression, suggesting potential to promote hair growth.
36 citations
,
October 2015 in “Journal of Cosmetic Dermatology” In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.