February 1956 in “Bulletin of Experimental Biology and Medicine” Glycogen levels in mouse skin drop after injury but increase during healing, returning to normal within a month.
773 citations,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
305 citations,
November 2016 in “International Journal of Biological Macromolecules” Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
252 citations,
July 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
185 citations,
October 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
124 citations,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
117 citations,
August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
86 citations,
June 2017 in “Anais Brasileiros de Dermatologia” Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
79 citations,
October 2015 in “Journal of Dermatological Treatment” Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.
64 citations,
September 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
53 citations,
May 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
51 citations,
October 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
40 citations,
February 2019 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
40 citations,
August 2014 in “Journal of Nanoparticle Research” Silver nanoparticles in gel form can effectively heal wounds.
34 citations,
September 2020 in “Clinical, cosmetic and investigational dermatology” Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
33 citations,
April 2017 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.
31 citations,
May 2018 in “Plastic and Reconstructive Surgery” PRP therapy may improve skin and hair conditions, but more research with standard methods is needed.
30 citations,
June 2016 in “Journal of Human Genetics” Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.
28 citations,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
28 citations,
January 1989 in “Toxicologic Pathology” Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
26 citations,
November 2016 in “European Journal of Clinical Pharmacology” Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
25 citations,
March 2017 in “Archives of Dermatological Research” Sinapic acid may help hair growth by activating a specific cell pathway.
25 citations,
September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
25 citations,
March 2012 in “Journal of oncology pharmacy practice” An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
23 citations,
February 2021 in “Journal of Endocrinological Investigation” Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
21 citations,
September 2015 in “Journal of the European Academy of Dermatology and Venereology” Yellow and orange colors are important for diagnosing certain skin conditions.
20 citations,
December 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
18 citations,
May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
17 citations,
April 2020 in “Dermatology and Therapy” The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.
17 citations,
January 2018 in “Journal of cutaneous and aesthetic surgery” The article discusses debates on hair transplant techniques, safe donor areas, PRP use, and practitioner qualifications in hair restoration.