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Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride use during early pregnancy may cause limb deformities in babies.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Baby born healthy despite mom taking finasteride, but more research needed.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

Finasteride negatively affects fish reproduction and gonadal development.

Finasteride and Dutasteride can improve hair growth in male baldness but may cause temporary sexual dysfunction and possibly affect fertility.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.

Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Gene mutations can cause problems in male genital development.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

The document is a detailed medical reference on skin and genetic disorders.