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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.